127-90-2

Basic information

• Product Name: Bis(2,3,3,3-tetrachloropropyl) ether
• Synonyms: OCTACHLORODIPROPYL ETHER;S 421;1,1’-oxybis(2,3,3,3-tetrachloro-Propane;ENT 25,456;ent25,456;Ether, bis(2,3,3,3-tetrachloropropyl);ether,bis(2,3,3,3-tetrachloropropyl);Monsanto 16226
• CAS NO: 127-90-2
• Molecular Formula: C₆H₆Cl₈O
• Molecular Weight: 377.74
• EINECS: 204-870-4
• Product Categories: Intermediates of Dyes and Pigments;Aliphatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 127-90-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: -49.9°C
• Boiling Point: 365.079 °C at 760 mmHg
• Flash Point: 177 °C
• Appearance: /
• Density: 1.6352 (estimate)
• Vapor Pressure: 3.38E-05mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: 0-6°C
• CAS DataBase Reference: Bis(2,3,3,3-tetrachloropropyl) ether(CAS DataBase Reference)
• NIST Chemistry Reference: Bis(2,3,3,3-tetrachloropropyl) ether(127-90-2)
• EPA Substance Registry System: Bis(2,3,3,3-tetrachloropropyl) ether(127-90-2)

Safety Data

• WGK Germany: 2
• RTECS: KN3600000
• Hazardous Substances Data: 127-90-2(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 127-90-2 differently. You can refer to the following data:
1. Bis(2,3,3,3-tetrachloropropyl) ether is an effective synergizing agent which is used in pesticide production.
2. S 421 is an effective synergizing agent which is used in pesticide production.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 44, p. 594, 2001 DOI: 10.1021/jm000282dTetrahedron Letters, 14, p. 1105, 1973

Safety Profile

Moderately toxic by ingestion.When heated to decomposition it emits toxic fumes ofClí. See also ETHERS and CHLORINATEDHYDROCARBONS, ALIPHATIC

InChI:InChI=1/C6H6Cl8O/c7-3(5(9,10)11)1-15-2-4(8)6(12,13)14/h3-4H,1-2H2

Synthetic route

bis(2-chloromethyl)ether (542-88-1) + Trichloroethylene (79-01-6) → 2,3,3,3,2',3',3',3'-Octachlorodipropyl ether (127-90-2)

Conditions	Yield
With aluminium trichloride

1,3,5-Trioxan (110-88-3) + aluminium trichloride (7446-70-0) + Trichloroethylene (79-01-6) → 2,3,3,3-tetrachloro-propan-1-ol (59778-03-9) + 2,3,3,3,2',3',3',3'-Octachlorodipropyl ether (127-90-2) + 2,3-dichloropropionyl chloride (7623-13-4)

formaldehyd (50-00-0) + aluminium trichloride (7446-70-0) + Trichloroethylene (79-01-6) → 2,3,3,3-tetrachloro-propan-1-ol (59778-03-9) + 2,3,3,3,2',3',3',3'-Octachlorodipropyl ether (127-90-2) + 2,3-dichloropropionyl chloride (7623-13-4)

2,3,3,3,2',3',3',3'-Octachlorodipropyl ether (127-90-2) → bis-(2,3,3-trichloro-allyl)-ether (69925-26-4)

Conditions	Yield
With potassium hydroxide

ethanol (64-17-5) + 2,3,3,3,2',3',3',3'-Octachlorodipropyl ether (127-90-2) + aqueous KOH-solution → bis-(2,3,3-trichloro-allyl)-ether (69925-26-4)

Upstream product

• 542-88-1 bis(2-chloromethyl)ether 
• 79-01-6 Trichloroethylene 
• 110-88-3 1,3,5-Trioxan 
• 7446-70-0 aluminium trichloride 
• 50-00-0 formaldehyd