127053-50-3Relevant articles and documents
DBU-Catalyzed Ring-Opening and Retro-Claisen Fragmentation of Dihydropyranones
Axelsson, Anton,Hammarvid, Emmelie,Rahm, Martin,Sundén, Henrik
, p. 5436 - 5444 (2020/08/26)
We present a general protocol for the formal Michael addition of acetone to α,β-unsaturated esters and amides, a transformation difficult to perform using current methods. The protocol comprises of an amidine catalyzed relay ring-opening and fragmentation
Highly effective vinylogous Mukaiyama-Michael reaction catalyzed by silyl methide species generated from 1,1,3,3-tetrakis(trifluoromethanesulfonyl)propane
Takahashi, Arata,Yanai, Hikaru,Zhang, Min,Sonoda, Takaaki,Mishima, Masaaki,Taguchi, Takeo
supporting information; experimental part, p. 1259 - 1265 (2010/04/29)
(Chemical Equation Presented) Silyl methide species in situ generated from 1,1,3,3-tetrakis(trifluoromethanesulfonyl)propane (Tf2CHCH 2CHTf2) performed as an excellent acid catalyst for the vinylogousMukaiyama-Michael reaction of α,β-unsaturated ketones with 2-silyloxyfurans. Notably, the required loading of Tf2CHCH 2CHTf2 to obtain the 1,4-adducts in reasonable yield was significantly low (from 0.05 to 1.0 mol%). This carbon acid-mediatedVMMreaction provides a powerful synthetic methodology to construct highly substituted γ-butenolide structure. 2010 American Chemical Society.
NOVEL REFORMATSKY REACTIONS OF 3-ARYLMETHYLENE-4,5-DIHYDRO-2(3H)-FURANONES AND 4-ARYLMETHYLENE-3-METHYL-5(4H)-ISOXAZOLONES
Batra, Sanjay,De, Dibyendu,Seth, Manju,Bhaduri, Amiya Prasad
, p. 1228 - 1238 (2007/10/02)
New avenues for enlarging the scope of Reformatsky reaction have been explored by reacting the title compounds with α-halogenoalkanoates in the presence of zinc.