127060-75-7

Basic information

• Product Name: CGP 42112
• Synonyms: [N-ALPHA-(NICOTINOYL-L-TYROSYL)-N-EPSILON-(N-ALPHA-Z-L-ARGINYL)-L-LYSYL]-L HISTIDYL-L-PROLYL-L-ISOLEUCINE;N-ALPHA-NICOTINOYL-TYR-LYS(N-ALPHA-CBZ-ARG)-HIS-PRO-ILE;N-ALPHA-NICOTINOYL-TYR-(N-ALPHA-CBZ-ARG)-LYS-HIS-PRO-ILE-OH;NICOTINOYL-TYR-LYS(CBZ-ARG)-HIS-PRO-ILE;NICOTINOYL-TYR-LYS(Z-ARG)-HIS-PRO-ILE-OH;NIC-TYR-LYS(Z-ARG)-HIS-PRO-ILE;CGP 42112;CGP-42112A
• CAS NO: 127060-75-7
• Molecular Formula: C52H69N13O11
• Molecular Weight: 1052.18
• Mol File: 127060-75-7.mol
• Article Data: 0

Chemical Properties

• Appearance: white/solid
• Density: 1.39 g/cm³
• Refractive Index: 1.659
• Storage Temp.: 2-8°C
• BRN: 8184948
• CAS DataBase Reference: CGP 42112(CAS DataBase Reference)
• NIST Chemistry Reference: CGP 42112(127060-75-7)
• EPA Substance Registry System: CGP 42112(127060-75-7)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 127060-75-7(Hazardous Substances Data)

Usage

Biochem/physiol Actions

Potent AT2 angiotensin II receptor agonist.

InChI:InChI=1/C52H69N13O11/c1-3-32(2)43(50(73)74)64-48(71)42-17-11-25-65(42)49(72)41(27-36-29-56-31-59-36)62-46(69)39(60-47(70)40(26-33-18-20-37(66)21-19-33)61-44(67)35-14-9-22-55-28-35)15-7-8-23-57-45(68)38(16-10-24-58-51(53)54)63-52(75)76-30-34-12-5-4-6-13-34/h4-6,9,12-14,18-22,28-29,31-32,38-43,66H,3,7-8,10-11,15-17,23-27,30H2,1-2H3,(H,56,59)(H,57,68)(H,60,70)(H,61,67)(H,62,69)(H,63,75)(H,64,71)(H,73,74)(H4,53,54,58)/t32-,38-,39-,40-,41-,42-,43-/m0/s1

Related news

Increased non-angiotensin II [125I] CGP 42112 (cas 127060-75-7) binding in rat carotid artery after balloon injury08/01/2019

In this study, [125I] CGP 42112, a ligand of high affinity and selectivity for the angiotensin II AT2 receptor, was used to detect and quantify a non-angiotensin II binding site in the balloon-injured carotid artery of the rat. The amount of [125I] CGP 42112 binding was significantly enhanced in...detailed