1270914-58-3 Usage
Description
Methyl 3-((2-aminophenyl)amino)propanoate is a chemical compound with the molecular formula C11H15NO2. It is a white crystalline powder that is a derivative of propanoic acid with a methyl ester group and an amino group attached to the phenyl ring. methyl 3-((2-aminophenyl)amino)propanoate is used in the pharmaceutical industry as a precursor in the synthesis of various drugs and pharmaceuticals. Its presence as a potential substrate for enzymatic reactions and its possible biological activity in certain contexts make it a valuable compound in organic synthesis and as a chemical intermediate in the production of other compounds.
Uses
Used in Pharmaceutical Industry:
Methyl 3-((2-aminophenyl)amino)propanoate is used as a precursor in the synthesis of various drugs and pharmaceuticals for its ability to be a building block in creating complex molecular structures.
Used in Organic Synthesis:
Methyl 3-((2-aminophenyl)amino)propanoate is used as a reagent in organic synthesis, facilitating the creation of a wide range of chemical compounds due to its versatile molecular structure.
Used as a Chemical Intermediate:
In the production of other compounds, methyl 3-((2-aminophenyl)amino)propanoate serves as a chemical intermediate, playing a crucial role in the synthesis of various end products.
Used in Enzymatic Reactions:
The presence of the amino group in methyl 3-((2-aminophenyl)amino)propanoate makes it a potential substrate for enzymatic reactions, which can be harnessed for specific biological or chemical processes.
Used for Biological Activity:
Methyl 3-((2-aminophenyl)amino)propanoate may exhibit biological activity in certain contexts, making it a candidate for further research and development in the field of biochemistry and pharmacology.
Check Digit Verification of cas no
The CAS Registry Mumber 1270914-58-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,7,0,9,1 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1270914-58:
(9*1)+(8*2)+(7*7)+(6*0)+(5*9)+(4*1)+(3*4)+(2*5)+(1*8)=153
153 % 10 = 3
So 1270914-58-3 is a valid CAS Registry Number.
1270914-58-3Relevant articles and documents
Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains
Taylor, Alexander M.,Vaswani, Rishi G.,Gehling, Victor S.,Hewitt, Michael C.,Leblanc, Yves,Audia, James E.,Bellon, Steve,Cummings, Richard T.,Co?té, Alexandre,Harmange, Jean-Christophe,Jayaram, Hari,Joshi, Shivangi,Lora, Jose M.,Mertz, Jennifer A.,Neiss, Adrianne,Pardo, Eneida,Nasveschuk, Christopher G.,Poy, Florence,Sandy, Peter,Setser, Jeremy W.,Sims, Robert J.,Tang, Yong,Albrecht, Brian K.
supporting information, p. 145 - 150 (2016/03/01)
Inhibition of the bromodomains of the BET family, of which BRD4 is a member, has been shown to decrease myc and interleukin (IL) 6 in vivo, markers that are of therapeutic relevance to cancer and inflammatory disease, respectively. Herein we report substituted benzo[b]isoxazolo[4,5-d]azepines and benzotriazolo[4,3-d][1,4]diazepines as fragment-derived novel inhibitors of the bromodomain of BRD4. Compounds from these series were potent and selective in cells, and subsequent optimization of microsomal stability yielded representatives that demonstrated dose- and time-dependent reduction of plasma IL-6 in mice.
