127117-42-4 Usage
Chemical compound
2-azabicyclo[3.1.0]hexane-1-carboxylic acid hydrochloride
Derivative of carboxylic acid
It is a derivative of carboxylic acid
Building block
Commonly used as a building block in the synthesis of pharmaceutical compounds
Bicyclic structure
It has a bicyclic structure
Heterocyclic compound
Contains a nitrogen atom, making it a heterocyclic compound
Hydrochloride salt form
More water-soluble and suitable for use in pharmaceutical formulations
Pharmacological properties
This compound may have various pharmacological properties due to its structural features
Drug discovery and development
Of interest in drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 127117-42-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,1,1 and 7 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 127117-42:
(8*1)+(7*2)+(6*7)+(5*1)+(4*1)+(3*7)+(2*4)+(1*2)=104
104 % 10 = 4
So 127117-42-4 is a valid CAS Registry Number.
127117-42-4Relevant articles and documents
Synthesis of (+/-)-2,3-Methanoproline: A Novel Inhibitor of Ethylene Biosynthesis
Switzer, Frank L.,Halbeek, Herman Van,Holt, Elizabeth M.,Stammer, Charles H.,Saltveit, Mikal E.
, p. 6091 - 6100 (2007/10/02)
The title compound, 2-aza-bicyclohexane-1-carboxylic acid (2) was prepared by treatment of N-benzyloxycarbonyl-2,3-dehydroproline tert-butyl ester with diazomethane followed by photolysis of the resulting pyrazoline and deprotection.Its N-acetyl-N'-methyl amide, a peptide mimic, was synthesized and the structure of was confirmed by X-ray diffraction studies.NMR spectroscopy was also used to examine the effect of the cyclopropane ring on its conformation.This 2,3-methanoamino acid (2) was found to be a weak inhibitor of ethylene biosynthesis in cucumber cotyledon strips and germinating squash seeds.The data show that 2 probably inhibits the conversion of 1-aminocyclopropanecarboxylic acid to ethylene in these tissues.
