127279-73-6 Usage
General Description
(1R,2S,3S,5S)-8-Methyl-3-(4-nitro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester is a chemical compound with a complex molecular structure. It is a methyl ester derivative of a bicyclic octane compound, containing a substituted nitrophenyl group. (1R,2S,3S,5S)-8-METHYL-3-(4-NITRO-PHENYL)-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER likely possesses pharmacological or biological activity due to its unique structure, making it potentially useful in various applications, such as in medicinal chemistry or as a research tool in biological studies. Further research and analysis would be necessary to fully understand its properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 127279-73-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,2,7 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 127279-73:
(8*1)+(7*2)+(6*7)+(5*2)+(4*7)+(3*9)+(2*7)+(1*3)=146
146 % 10 = 6
So 127279-73-6 is a valid CAS Registry Number.
127279-73-6Relevant articles and documents
Synthesis, ligand binding, QSAR, and CoMFA study of 3β-(p-substituted phenyl)tropane-2β-carboxylic acid methyl esters
Carroll,Gao,Rahman,Abraham,Parham,Lewin,Boja,Kuhar
, p. 2719 - 2725 (2007/10/02)
A series of 3β-(p-substituted phenyl)tropane-2β-carboxylic acid methyl esters (2) were synthesized and found to possess high affinity for the cocaine binding site in rat striatum. The p-chloro (2c) and p-iodo (2n) compounds, which were the most potent analogues prepared, were found to be 85 and 78 times more potent than (-)-cocaine. The p-bromo (2m) and p-methyl (2d) were also 56 and 60 times more potent than cocaine. QSAR and CoMFA studies were conducted to correlate binding affinity of the cocaine analogues with their structural features. Whereas the QSAR study gave relatively low correlations, the CoMFA study gave a correlation with high predictive value.
