127399-79-5

Basic information

• Product Name: 2-(benzyloxy)-1,6-dibromonaphthalene
• Synonyms: 2-(benzyloxy)-1,6-dibromonaphthalene
• CAS NO: 127399-79-5
• Molecular Weight: 392.09
• Mol File: 127399-79-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(benzyloxy)-1,6-dibromonaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzyloxy)-1,6-dibromonaphthalene(127399-79-5)
• EPA Substance Registry System: 2-(benzyloxy)-1,6-dibromonaphthalene(127399-79-5)

Safety Data

• Hazardous Substances Data: 127399-79-5(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 16239-18-2 1,6-dibromo-2-naphthol 
• 100-44-7 benzyl chloride 

Downstream Products

• 1365958-40-2 2-(benzyloxy)-6-(3-(benzyloxy)phenyl)-1-bromonaphthalene 
• 1365958-07-1 N-(3-(2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl)phenyl)-3-methylbenzenesulfonamide 
• 1365958-04-8 N-(3-(2-(hydroxy)-6-(3-(hydroxy)phenyl)naphthalen-1-yl)phenyl)-2-methylbenzenesulfonamide 
• 1365958-01-5 N-(3-(2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl)phenyl)-4-hydroxybenzenesulfonamide 
• 1365957-98-7 N-(3-(2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl)phenyl)-3-hydroxybenzenesulfonamide 
• 1365957-96-5 N-(3-(2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl)phenyl)-4-fluorobenzenesulfonamide 
• 1365957-94-3 N-(3-(2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl)phenyl)-3-fluorobenzenesulfonamide 
• 1365957-92-1 N-(3-(2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl)phenyl)-2-fluorobenzenesulfonamide 
• 1365957-90-9 N-(3-(2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl)phenyl)-4-cyanobenzenesulfonamide 
• 1365957-87-4 N-(3-(2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl)phenyl)-3-cyanobenzenesulfonamide 
• 1365957-85-2 N-(3-(2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl)phenyl)-2,4-dinitrobenzenesulfonamide 
• 1365957-83-0 N-(3-(2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl)phenyl)-2-nitrobenzenesulfonamide 
• 1365957-80-7 N-(3-(2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl)phenyl)benzenesulfonamide 
• 1365959-02-9 N-(3-(2-(benzyloxy)-6-(3-(benzyloxy)phenyl)naphthalen-1-yl)phenyl)-2,2,2-trifluoroethanesulfonamide 

Relevant articles and documents

Rh(II)-Catalyzed Synthetic Strategy for Diverse and Functionalized Halonaphthalenyl Ethers and Esters from Diazo Compounds and Its Application to Polyaromatic Compounds

An efficient and simple synthesis of various functionalized halonaphthalenyl ethers and esters in moderate to good yield was achieved via rhodium(II)-catalyzed reaction of readily available diazo compounds with benzyl halides or acid halides. This methodology has several advantages, such as ease of handling, mild reaction conditions, bromine- or chlorine-free route, and the use of an effective catalyst. The synthesized compounds were further converted into valuable polyaromatic compounds using the Suzuki reaction.

Monomethyl Ether Derivatives of 7,8-Dihydroxy- and 8,9-Dihydroxy-4-n-propyl-1,2,3,4,4a,5,6,10b-octahydrobenzoquinolines as Possible Products of Metabolism by Catechol-O-methyltransferase

In order to facilitate identification of possible metabolites arising from in vitro action of catechol-O-methyltransferase upon 7,8-dihydroxy- and 8,9-dihydroxy-4-n-propyl-1,2,3,4,4a,5,6,10b-octahydrobenzoquinolines (11, 12), all four possible monomethyl ether derivatives have been synthesized.Incubation of 11 and 12 with the enzyme revealed that the 8,9-dihydroxy positional isomer 12 (which contains the dopamine moiety held in the β conformation) but not the 7,8-dihydroxy isomer 11 (which holds the dopamine moiety in the α conformation) was a substrate for theenzyme.The sole detectable product of 12 was 8-hydroxy-9-methoxy derivative 15 in which the "meta" hydroxy group of the dopamine moiety is etherified.