127425-73-4

Basic information

• Product Name: 3-Fluoro-4-bromobenzyl bromide
• Synonyms: 3-Fluoro-4-bromobenzyl bromide;1-Bromo-4-(bromomethyl)-2-fluorobenzene, alpha,4-Dibromo-3-fluorotoluene;4-Bromo-3-fluorobenzyl bromide 97%;4-BroMo-1-(broMoMethyl)-3-fluorobenzene
• CAS NO: 127425-73-4
• Molecular Formula: C₇H₅Br₂F
• Molecular Weight: 267.93
• Product Categories: alkyl bromide| alkyl Fluorine
• Mol File: 127425-73-4.mol
• Article Data: 26

Chemical Properties

• Melting Point: 33-36℃
• Boiling Point: 252℃
• Flash Point: 106℃
• Appearance: /
• Density: 1.923
• Vapor Pressure: 0.0205mmHg at 25°C
• Refractive Index: 1.583
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-Fluoro-4-bromobenzyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Fluoro-4-bromobenzyl bromide(127425-73-4)
• EPA Substance Registry System: 3-Fluoro-4-bromobenzyl bromide(127425-73-4)

Safety Data

• HazardClass: 8
• Hazardous Substances Data: 127425-73-4(Hazardous Substances Data)

Usage

Chemical Properties

light yellow liquid

InChI:InChI=1/C7H5Br2F/c8-4-5-1-2-7(10)6(9)3-5/h1-3H,4H2

Upstream product

• 452-74-4 4-bromo-3-fluorotoluene 
• 34241-39-9 azobisisobutyronitrile 
• 133059-43-5 4-bromo-3-fluorobenzaldehyde 
• 222978-01-0 4-bromo-3-fluorobenzyl alcohol 

Downstream Products

• 499983-13-0 2-( 4-bromo-3-fluorophenyl)acetonitrile 
• 942282-40-8 2-(4-bromo-3-fluorophenyl)acetic acid 
• 942282-41-9 methyl 2-(4-bromo-3-fluorophenyl)acetate 
• 1259022-70-2 methyl 2-(3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate 
• 133059-43-5 4-bromo-3-fluorobenzaldehyde 

Relevant articles and documents

AROMATIC ACETYLENE OR AROMATIC ETHYLENE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF

Disclosed are an aromatic acetylene or aromatic ethylene compound, an intermediate, a preparation method, a pharmaceutical composition and a use thereof. The aromatic acetylene or aromatic ethylene compound has a significant inhibitory effect on PD-1 and PD-L1, and can effectively relieve or treat cancers and other related diseases.

INHIBITORS OF FATTY ACID AMIDE HYDROLASE

The present invention provides compounds, and pharmaceutically acceptable compositions thereof, encompassed by any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof. The present invention also provides methods for treating an FAAH mediated disease, disorder or condition by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof. Additionally, the present invention provides methods for inhibiting FAAH by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof.

PYRROLIDINYL SULFONE RORGAMMA MODULATORS

Described are RORγ modulators of the formula (I), or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.