128134-29-2Relevant articles and documents
D-3,4-'cyclopropylglutamate' isomers as nmda receptor ligands: Synthesis and enantioselective activity
Pellicciari, Roberto,Natalini, Benedetto,Marinozzi, Maura,Monahan, Joseph B.,Snyder, James P.
, p. 139 - 142 (1990)
Dirhodium(II) tetraacetate catalyzed decomposition of ethyl diazoacetate in the presence of D-Cbz-vinylglycine methyl ester (11) afforded a mixture of the cyclopropyl esters D-CGA A-D (13) from which the corresponding 2R-acids 7-10 were obtained and their absolute configurations assigned. The (2R,3S,4R) α-(carboxycyclopropyl)glycine (D-CGA C, 9 resulted to be the most potent and selective among the NMDA receptor ligands yet reported.