1281922-74-4Relevant articles and documents
Stereoselective synthesis of MLN4924, an inhibitor of NEDD8-activating enzyme
Lee, Hyuk Woo,Nam, Soo Kyung,Choi, Won Jun,Kim, Hea Ok,Jeong, Lak Shin
, p. 3557 - 3561 (2011)
MLN4924 (1), which is in clinical trials as an anticancer agent, was stereoselectively synthesized from d-ribose via a route involving stereoselective reduction, regioselective cleavage of an isopropylidene moiety, and selective displacement of a cyclic s