128373-20-6

Basic information

• Product Name: [4-(Furan-2-yl)phenyl](phenyl)methanone
• Synonyms: [4-(Furan-2-yl)phenyl](phenyl)methanone
• CAS NO: 128373-20-6
• Molecular Formula: C17H12O2
• Molecular Weight: 248
• Mol File: 128373-20-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 80-82℃
• Appearance: /
• CAS DataBase Reference: [4-(Furan-2-yl)phenyl](phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(Furan-2-yl)phenyl](phenyl)methanone(128373-20-6)
• EPA Substance Registry System: [4-(Furan-2-yl)phenyl](phenyl)methanone(128373-20-6)

Safety Data

• Hazardous Substances Data: 128373-20-6(Hazardous Substances Data)

Usage

General Description

[4-(Furan-2-yl)phenyl](phenyl)methanone is a chemical compound with the molecular formula C17H12O. It is a ketone derivative, containing a furan-2-yl moiety and two phenyl groups. [4-(Furan-2-yl)phenyl](phenyl)methanone is commonly used as a building block in organic synthesis and pharmaceutical research. It is known for its potential use in the development of new drugs and therapeutic agents due to its unique chemical structure and reactivity. Additionally, studies have shown that [4-(Furan-2-yl)phenyl](phenyl)methanone exhibits bioactive properties, making it a topic of interest in medicinal chemistry and drug discovery.

Upstream product

• 110-00-9 furan 
• 134-85-0 4-chlorobenzophenone 
• 81745-86-0 2-furylzinc chloride 
• 31688-74-1 p-PhC(O)C₆H₄NMe₃(+)*I(-) 

Relevant articles and documents

Continuous Visible-Light Photoflow Approach for a Manganese-Catalyzed (Het)Arene C?H Arylation

Manganese photocatalysts enabled versatile room-temperature C?H arylation reactions by means of continuous visible-light photoflow, thus allowing for efficient C?H arylations in 30 minutes with ample scope. The robustness of the manganese-catalyzed photoflow strategy was shown by visible light-induced gram-scale synthesis, clearly outperforming the batch performance.

Cross-coupling of aryltrimethylammonium iodides with arylzinc reagents catalyzed by amido pincer nickel complexes

The cross-coupling reaction of aryltrimethylammonium iodides with aryl- or heteroarylzinc chlorides catalyzed by amido pincer nickel complexes was performed. The reaction requires low catalyst loading and displays broad substrate scope.

Palladium-catalyzed indole, pyrrole, and furan arylation by aryl chlorides

The palladium-catalyzed direct arylation of indoles, pyrroles, and furans by aryl chlorides has been demonstrated. The method employs a palladium acetate catalyst, 2-(dicyclohexylphosphino)-biphenyl ligand, and an inorganic base. Electron-rich and electron-poor aryl chlorides as well as chloropyridine coupling partners can be used, and arylated heterocycles are obtained in moderate to good yields. Optimization of base, ligand, and solvent is required for achieving best results.