1285513-32-7 Usage
General Description
2-(benzyloxy)-5-bromo-N-(pyridin-3-yl)benzamide is a chemical compound with the molecular formula C21H17BrN2O2. It is a benzamide derivative and contains a bromo and a pyridin-3-yl group. 2-(benzyloxy)-5-bromo-N-(pyridin-3-yl)benzamide is a potential drug candidate due to its pharmacological properties. It may have uses in the field of medicinal chemistry, particularly in the development of new medications for various diseases. Further research and studies are needed to fully understand the potential applications and effects of this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 1285513-32-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,8,5,5,1 and 3 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1285513-32:
(9*1)+(8*2)+(7*8)+(6*5)+(5*5)+(4*1)+(3*3)+(2*3)+(1*2)=157
157 % 10 = 7
So 1285513-32-7 is a valid CAS Registry Number.
1285513-32-7Relevant articles and documents
Discovery of 5-substituent-N-arylbenzamide derivatives as potent, selective and orally bioavailable LRRK2 inhibitors
Ding, Xiao,Dai, Xuedong,Long, Kai,Peng, Cheng,Andreotti, Daniele,Bamborough, Paul,Eatherton, Andrew J.,Edge, Colin,Jandu, Karamjit S.,Nichols, Paula L.,Philps, Oliver J.,Stasi, Luigi Piero,Wan, Zehong,Xiang, Jia-Ning,Dong, Kelly,Dossang, Pamela,Ho, Ming-Hsun,Li, Yi,Mensah, Lucy,Guan, Xiaoming,Reith, Alastair D.,Ren, Feng
, p. 4034 - 4038 (2017/08/23)
Leucine-rich repeat kinase 2 (LRRK2) has been suggested as a potential therapeutic target for Parkinson's disease. Herein we report the discovery of 5-substituent-N-arylbenzamide derivatives as novel LRRK2 inhibitors. Extensive SAR study led to the discovery of compounds 8e, which demonstrated potent LRRK2 inhibition activity, high selectivity across the kinome, good brain exposure, and high oral bioavailability.