128942-81-4Relevant articles and documents
Regiospecific Hydroamination of Unsymmetrical Electron-Rich and Electron-Poor Alkynes with Anilines Catalyzed by Gold(I) Immobilized in MCM-41
Liu, Dayi,Nie, Quan,Zhang, Rongli,Cai, Mingzhong
supporting information, p. 3940 - 3948 (2018/09/14)
The first heterogeneous gold(I)-catalyzed regiospecific hydroamination of ynamides and propiolic acid derivatives with anilines has been achieved by using a diphenylphosphine-functionalized MCM-41-supported gold (I) complex and AgNTf2 as catalysts under mild conditions, yielding the corresponding (E)-N-arylimines and (Z)-enamines in good to excellent yields with broad substrate scope. The new heterogeneous gold(I) complex can easily be prepared via a two-step procedure from commercially available reagents and recovered by simple filtration of the reaction mixture. The recovered catalyst (Ph2P-MCM-41-AuNTf2) can be reused at least seven times without addition of AgNTf2 as a co-catalyst and its catalytic efficiency remains unaltered. (Figure presented.).
Copper-catalyzed aerobic intramolecular carbo- and amino-oxygenation of alkynes for synthesis of azaheterocycles
Toh, Kah Kah,Sanjaya, Stephen,Sahnoun, Sophian,Chong, Sin Yee,Chiba, Shunsuke
supporting information; experimental part, p. 2290 - 2292 (2012/06/30)
A synthetic method of highly substituted quinolines has been developed from N-(2-alkynylaryl)enamine carboxylates under Cu-catalyzed aerobic conditions via intramolecular carbo-oxygenation of alkynes. This strategy was further applied for N-alkynylamidine
Novel synthesis of fused indoles and 2-substituted indoles by the palladium-catalyzed cyclization of N-cycloalkenyl-o-haloanilines
Maruyama, Jun,Yamashita, Hiromichi,Watanabe, Takeshi,Arai, Shigeru,Nishida, Atsushi
experimental part, p. 1327 - 1335 (2009/04/10)
A new palladium-catalyzed cyclization of N-alkenyl-o-haloanilines with selective isomerization of a double bond followed by formal 5-endo-trig cyclization was developed. A variety of fused and 2-substituted indoles were synthesized from enaminoesters prepared by condensation of β-ketoesters and o-iodoaniline.
