129043-04-5 Usage
Description
(S)-3-AMINO-3-(3-PYRIDYL)-PROPIONIC ACID, also known as (S)-3-Amino-3-(3-pyridyl)propionic acid, is an organic compound with a unique structure that features an amino group and a pyridyl group. It plays a crucial role in various biochemical processes and has potential applications in different industries due to its specific properties.
Uses
Used in Pharmaceutical Industry:
(S)-3-AMINO-3-(3-PYRIDYL)-PROPIONIC ACID is used as an amino-donor in the transamination process for the degradation of (S)-β-phenylalanine. This application is significant in the pharmaceutical industry as it aids in the synthesis of various pharmaceutical compounds and contributes to the development of new drugs.
Used in Biochemical Research:
In the field of biochemical research, (S)-3-AMINO-3-(3-PYRIDYL)-PROPIONIC ACID serves as an essential compound for studying the mechanisms of transamination reactions. This knowledge can be applied to understand the metabolic pathways and develop targeted therapies for various diseases.
Used in Chemical Synthesis:
(S)-3-AMINO-3-(3-PYRIDYL)-PROPIONIC ACID is also used as a key intermediate in the synthesis of various chemical compounds, particularly those with potential applications in the pharmaceutical, agrochemical, and material science industries. Its unique structure allows for the development of novel molecules with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 129043-04-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,0,4 and 3 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 129043-04:
(8*1)+(7*2)+(6*9)+(5*0)+(4*4)+(3*3)+(2*0)+(1*4)=105
105 % 10 = 5
So 129043-04-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O2/c9-7(4-8(11)12)6-2-1-3-10-5-6/h1-3,5,7H,4,9H2,(H,11,12)/t7-/m0/s1
129043-04-5Relevant articles and documents
Iridium-catalysed C-H borylation of β-aryl-aminopropionic acids
MacDonald, Simon J. F.,Nortcliffe, Andrew,Robinson, Henry,Simelis, Klemensas,Stillibrand, Joe
supporting information, p. 6696 - 6701 (2020/09/21)
Iridium-catalysed catalytic, regioselective C-H borylation of β-aryl-aminopropionic acid derivatives gives access to 3,5-functionalised protected β-aryl-aminopropionic acid boronates. The synthetic versatility of these new boronates is demonstrated through sequential one-pot functionalisation reactions to give diverse building blocks for medicinal chemistry. The C-H borylation is also effective for dipeptide substrates. We have exemplified this methodology in the synthesis of a pan αv integrin antagonist.
Burkholderia cepacia lipase is an excellent enzyme for the enantioselective hydrolysis of β-heteroaryl-β-amino esters
Tasnadi, Gabor,Forro, Eniko,Fueloep, Ferenc
experimental part, p. 1771 - 1777 (2009/12/28)
The enantioselective (E >200) lipase PS-catalysed hydrolysis of β-heteroaryl-β-amino esters is described. The reactions were performed with H2O (0.5 equiv) in either diisopropyl ether or tert-butyl methyl ether at 25 °C. The resulting β-heteroaryl-substituted β-amino acid enantiomers were formed in high enantiomeric excess (ee ≥ 97%) and in good yield (≥40%).
Structure-activity relationships of 1,3,5-triazine-2,4,6-triones as human gonadotropin-releasing hormone receptor antagonists
Guo, Zhiqiang,Wu, Dongpei,Zhu, Yun-Fei,Tucci, Fabio C.,Regan, Collin F.,Rowbottom, Martin W.,Struthers, R. Scott,Xie, Qiu,Reijmers, Shelby,Sullivan, Susan K.,Sai, Yang,Chen, Chen
, p. 3685 - 3690 (2007/10/03)
SAR studies of 1,3,5-triazine-2,4,6-triones as human gonadotropin-releasing hormone receptor antagonists resulted in potent compounds. The best compound from the series had a binding affinity of 2 nM.