129050-23-3Relevant articles and documents
PROCESS FOR THE SYNTHESIS OF INTERMEDIATES OF NEBIVOLOL
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Page/Page column 32-34, (2017/08/20)
The present invention relates to a novel process for the synthesis of the intermediate compounds constituted by chromanyl haloketones of formula III and 6-fluoro-2-(oxiran-2-yl) chromans of formula I. The intermediates thus obtained can be used for the sy
PROCESS FOR THE PREPARATION OF NEBIVOLOL
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Page/Page column 21-22, (2012/07/28)
The present invention relates to a novel process for the synthesis of the Nebivolol product depicted in Scheme 1, comprised of a reduced number of high-yield steps, and characterized by the enzymatic resolution of the chroman ester precursor.
PROCESS FOR PREPARING NEBIVOLOL
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Page/Page column 24, (2008/12/06)
The present invention relates to a process for preparing Nebivolol and, more particularly, to an improved process for synthesizing enantiomerically enriched 6-fluoro chroman alcohol or epoxide derivatives of formula, wherein R and X is defined in the description; as useful intermediates in the preparation of Nebivolol.