129323-06-4

Basic information

• Product Name: 2-{3-[bis(1-methylethyl)amino]-2-hydroxypropoxy}-N-1H-indol-4-ylbenzamide
• CAS NO: 129323-06-4
• Molecular Formula: C₂₄H₃₁N₃O₃
• Molecular Weight: 409.5212
• Mol File: 129323-06-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 549.2°C at 760 mmHg
• Flash Point: 285.9°C
• Density: 1.195g/cm³
• Vapor Pressure: 6.8E-13mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: 2-{3-[bis(1-methylethyl)amino]-2-hydroxypropoxy}-N-1H-indol-4-ylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{3-[bis(1-methylethyl)amino]-2-hydroxypropoxy}-N-1H-indol-4-ylbenzamide(129323-06-4)
• EPA Substance Registry System: 2-{3-[bis(1-methylethyl)amino]-2-hydroxypropoxy}-N-1H-indol-4-ylbenzamide(129323-06-4)

Safety Data

• Hazardous Substances Data: 129323-06-4(Hazardous Substances Data)

Usage

Components

Isopropyl groups
Hydroxypropoxy group
Indol-4-ylbenzamide group
1H-indol group

Pharmacological properties

potential drug or pharmaceutical compound
Complex structure with functional groups that can interact with biological systems

Relevant articles and documents

N-(1H-INDOLE-4-YL)-BENZAMIDES

Novel indole carboxamides of the formula STR1 wherein R and R 1 are individually selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, cycloalkylalkyl of 4 to 7 carbon atoms and aralkyl of 7 to 12 carbon atoms optionally substituted with 1 to 3 members of the group consisting of halogen, methyl, ethyl, methoxy, ethoxy,--CF 3, CH 3 S--,--NH 2 and--NO 2 or R 1 and R taken together with the nitrogen atom form an optionally unsaturated heterocycle optionally containing a member of the group consisting of--O--,--S--and STR2 R' is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, phenyl, naphthyl, aralkyl of 7 to 12 carbon atoms and substituted phenyl, R 3 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, alkoxy of 1 to 3 carbon atoms, chlorine, bromine, iodine,--NO 2,--NH 2, acylamide of an aliphatic carboxylic acid of 2 to 5 carbon atoms and mono and dialkylamino with alkyl of 1 to 5 carbon atoms, a and b form =O and c is hydrogen or a and c form a carbon-carbon bond and b is hydrogen, A is selected from the group consisting of--(CH 2). sub.n--and STR3 n is an integer from 2 to 5, m is an integer from 1 to 3, B is STR4 R 2 is selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having remarkable anti-arrhytmic properties.