129488-00-2

Basic information

• Product Name: 6-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 6-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-Boc-6-amino-2,3-dihydroindole;tert-butyl 6-aminoindoline-1-carboxylate;1H-Indole-1-carboxylic acid, 6-aMino-2,3-dihydro-, 1,1-diMethylethyl ester;6-Aminoindoline-1-carboxylic acid tert-butyl ester;tert-Butyl 6-amino-2,3-dihydro-1H-indole-1-carboxylate;6-Amino-1-Boc-indoline
• CAS NO: 129488-00-2
• Molecular Formula: C₁₃H₁₈N₂O₂
• Molecular Weight: 234.29
• Mol File: 129488-00-2.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 374.947 °C at 760 mmHg
• Flash Point: 180.561 °C
• Appearance: /
• Density: 1.177±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.582
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 6-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 6-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(129488-00-2)
• EPA Substance Registry System: 6-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(129488-00-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 129488-00-2(Hazardous Substances Data)

Usage

General Description

6-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester is a chemical compound with the molecular formula C14H18N2O2. It is a tert-butyl ester derivative of 6-amino-2,3-dihydro-1H-indole-1-carboxylic acid, an important building block in the synthesis of pharmaceuticals and chemical compounds. 6-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is commonly used as a reagent in organic chemistry research and drug development. It has the potential to be utilized in the synthesis of various pharmaceutical and agrochemical compounds due to its versatile chemical properties.

InChI:InChI=1/C13H18N2O2/c1-13(2,3)17-12(16)15-7-6-9-4-5-10(14)8-11(9)15/h4-5,8H,6-7,14H2,1-3H3

Upstream product

• 496-15-1 1-indoline 
• 219552-64-4 tert-butyl 6-nitro-1H-indole-1-carboxylate 
• 219508-62-0 tert-butyl 6-amino-1H-indole-1-carboxylate 
• 545393-63-3 tert-butyl 6-(1-aza-2,2-diphenylvinyl)indolinecarboxylate 
• 129487-99-6 tert-butyl 6-nitroindoline-1-carboxylate 
• 19727-83-4 6-nitroindoline 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 848951-52-0 6-(1-benzyl-piperidin-4-ylamino)-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester 
• 219507-70-7 N-(1-Boc-6-indolinyl)-2-nitrobenzamide 
• 15918-79-3 indolin-6-amine 

Relevant articles and documents

INHIBITORS OF MUTANT ISOCITRATE DEHYDROGENASES AND COMPOSITIONS AND METHODS THEREOF

The invention provides novel chemical compounds useful for treating cancer, or a related disease or disorder thereof, and pharmaceutical composition and methods of preparation and use thereof.

LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS

The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4—P-M-M4??I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.

IMIDAZOLE DERIVATIVES AS FUNCTIONALLY SELECTIVE ALPHA2C ADRENORECEPTOR AGONISTS

In its many embodiments, the present invention provides imidazole derivatives which are inhibitors of alPha2C adrenergic receptor agonists, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition or amelioration of one or more conditions associated with the alpha2C adrenergic receptors using such compounds or pharmaceutical compositions. Formula (I).