129708-04-9

Basic information

• Product Name: 5-allyl-2-(benzyloxy)-3-methoxybenzaldehyde
• Synonyms: 5-allyl-2-(benzyloxy)-3-methoxybenzaldehyde
• CAS NO: 129708-04-9
• Molecular Weight: 282.339
• Mol File: 129708-04-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-allyl-2-(benzyloxy)-3-methoxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-allyl-2-(benzyloxy)-3-methoxybenzaldehyde(129708-04-9)
• EPA Substance Registry System: 5-allyl-2-(benzyloxy)-3-methoxybenzaldehyde(129708-04-9)

Safety Data

• Hazardous Substances Data: 129708-04-9(Hazardous Substances Data)

Upstream product

• 23343-06-8 2-allyloxy-3-methoxy-benzaldehyde 
• 22934-51-6 5-allyl-2-hydroxy-3-methoxybenzaldehyde 
• 100-39-0 benzyl bromide 

Downstream Products

• 129708-20-9 ethyl 1-(4-methoxyphenyl)-6-(benzyloxy)-2-methyl-5-methoxy-2,3-dihydro-1H-1,9-diazaphenalene-8-carboxylate 
• 133495-97-3 ethyl α-<(triphenylphosphoranylidene)amino>-5-allyl-2-(benzyloxy)-3-methoxycinnamate 
• 129708-11-8 ethyl α-azido-5-allyl-2-(benzyloxy)-3-methoxycinnamate 

Relevant articles and documents

Synthesis of Isoquinoline Derivatives by a Tandem Aza-Wittig/Electrocyclization Strategy and Preparation of the Unknown 1,9-Diazaphenalene Ring by a Consecutive Electrocyclic Ring Closure/Claisen Rearrangement/Intramolecular Amination Process

Treatment of iminophosphorane 3, derived from ethyl α-azido-2-(allyloxy)cinnamate, with aromatic isocyanates in toluene at 150 deg C leads to the corresponding isoquinoline derivatives 5 by a tandem electrocyclic ring closure/Claisen rearrangement of the intermediate carbodiimide.Fremy's salt promoted oxidation of compounds 5 yields the 5,8-isoquinolinequinone allides 6, which by heating undergo cyclization to 2H-pyranoisoquinolines 7.Iminophosphorane 14, derived from ethyl α-azido-2-(allyloxy)-3-methoxycinnamate, reacts with aromatic isocyanates to give thecorresponding carbodiimides, which by thermal treatment at 150 deg C undergo a consecutive electrocyclic ring closure/Claisen rearrangement/intramolecular amination process to give 1,9-diazaphenalene derivatives 18 in moderate yields.