130217-49-1

Basic information

• Product Name: Benzoic acid, 4-[(3-ethoxy-1,3-dioxopropyl)amino]-
• CAS NO: 130217-49-1
• Molecular Formula: C12H13NO5
• Molecular Weight: 251.239
• Mol File: 130217-49-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-[(3-ethoxy-1,3-dioxopropyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[(3-ethoxy-1,3-dioxopropyl)amino]-(130217-49-1)
• EPA Substance Registry System: Benzoic acid, 4-[(3-ethoxy-1,3-dioxopropyl)amino]-(130217-49-1)

Safety Data

• Hazardous Substances Data: 130217-49-1(Hazardous Substances Data)

Upstream product

• 138-84-1 potassium 4-aminobenzoate 
• 105-53-3 diethyl malonate 
• 150-13-0 4-amino-benzoic acid 
• 36239-09-5 ethyl chlorocarbonylacetate 

Downstream Products

• 55244-09-2 2-hydroxymalonanilic acid ethyl ester 
• 10256-16-3 N,N'-di-4-carboxyanilide of malonic acid 
• 105-53-3 diethyl malonate 

Relevant articles and documents

NOVEL ANILINE DERIVATIVES AND USE THEREOF

Aniline derivatives for anticancer treatment including a compound of the Formula 1, or a derivative thereof, as an active ingredient,

NOVEL ANILINE DERIVATIVES AND USE THEREOF

The present invention relates a novel aniline derivatives for anticancer and more particularly, it relates a novel aniline derivatives for anticancer comprising compound of the Formula 1 or a derivative thereof as an active ingredient. A compound of the present invention inhibits AIMP2-DX2 which is novel anticancer target and induces apoptosis of cancer cells, thereby being effective in preventing and treating cancer. Therefore, a novel aniline derivatives of the present invention can be used for preventing and treating cancer.

Ethyl Esters of Malonanilic Acids. Synthesis and Pyrolysis

The pyrolysis under 170-220 deg C or boiling in DMF of malonanilic acids ethyl esters (2) is accompanied by formation of malonic acids symmetric dianilides (7) with high yields.A possible mechanism for this transformation has been suggested.