130247-53-9

Basic information

• Product Name: Propanedioic acid, [(dimethylphenylsilyl)methylene]-, diethyl ester
• CAS NO: 130247-53-9
• Molecular Formula: C16H22O4Si
• Molecular Weight: 306.434
• Mol File: 130247-53-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [(dimethylphenylsilyl)methylene]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [(dimethylphenylsilyl)methylene]-, diethyl ester(130247-53-9)
• EPA Substance Registry System: Propanedioic acid, [(dimethylphenylsilyl)methylene]-, diethyl ester(130247-53-9)

Safety Data

• Hazardous Substances Data: 130247-53-9(Hazardous Substances Data)

Upstream product

• 72798-17-5 2-phenylsulfanylmethylene-malonic acid diethyl ester 
• 3839-31-4 dimethyl(phenyl)silyllithium 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 120097-60-1 Diethyl <(phenylsulfonyl)methylidene>malonate 
• 33668-60-9 iodo(dimethyl)(phenyl)silane 

Downstream Products

• 130247-62-0 ((E)-3-Allyl-non-1-enyl)-dimethyl-phenyl-silane 
• 504413-96-1 2-acetyl-3-(dimethyl-phenyl-silanyl)-4-ethoxycarbonyl-pentanedioic acid diethyl ester 
• 561063-96-5 ethyl 3-dimethyl(phenyl)silyl-2-ethoxycarbonyl-2-methyl-3-butenoate 
• 561063-99-8 ethyl 3-dimethyl(phenyl)silyl-2-ethoxycarbonyl-2-benzyl-3-butenoate 
• 1514833-22-7 (R)-4-(dimethyl(phenyl)silyl)pyrrolidine-2-one 

Relevant articles and documents

A Rapid and Efficient Synthesis of a Bifunctional β-Silylketone, Precursor for a Solid Supported β-Silylethanol Anchoring Group

A concise synthesis of 3-dimethyl(phenyl)silyl-5-oxo-hexanoic acid 1, the precursor for a solid supported β-silylethanol anchoring group has been achieved from ethyl 2-ethoxycarbonyl-3-dimethyl(phenyl)silyl-2-propenoate 2 featuring amino acid catalysed Mi

Preparation of functionalized Z-olefins using 1,1-dimetalloalkanes

1,1-Dimetalloalkanes obtained by the allylzincation of alkenylmagnesium compounds react smoothly with various functionalized alkylidenemalonates providing functionalized Z-olefins in good yields. If dimenthyl alkylidenemalonates are used, then excellent stereoselectivities are observed (92:8 to 100:0). An application to a short stereospecific synthesis of an insect pheromone [(Z)-7-dodecenyl acetate] is described (> 99.9% Z, 70% overall yield).