130517-90-7

Basic information

• Product Name: Butyric acid (1R,2R)-2-butyrylamino-1-carbamoyl-2-phenyl-ethyl ester
• CAS NO: 130517-90-7
• Molecular Weight: 320.389
• Mol File: 130517-90-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Butyric acid (1R,2R)-2-butyrylamino-1-carbamoyl-2-phenyl-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butyric acid (1R,2R)-2-butyrylamino-1-carbamoyl-2-phenyl-ethyl ester(130517-90-7)
• EPA Substance Registry System: Butyric acid (1R,2R)-2-butyrylamino-1-carbamoyl-2-phenyl-ethyl ester(130517-90-7)

Safety Data

• Hazardous Substances Data: 130517-90-7(Hazardous Substances Data)

Upstream product

• 106-31-0 butanoic acid anhydride 
• 55325-49-0 (±)-anti-3-amino-2-hydroxy-3-phenylpropanamide 

Relevant articles and documents

CHEMO-ENZYMATIC SYNTHESIS OF ALL ISOMERIC 3-PHENYLSERINES AND -ISOSERINES

The synthesis of all isomers of 3-phenylserines and 3-phenylisoserines in enantiomerically pure form is presented.Diastereomerically pure educts (threo/erythro-2-azido-3-butanoyloxy-3-phenyl-propionic esters, threo/erythro-3-azido-2-butanoyloxy-3-phenylpropionic esters, threo-2-butanoylamino-3-butanoyloxy-3-phenylpropionic ester, erythro-3-butanoylamino-2-butanoyloxy-3-phenyl-propionamide) were prepared from cinnamic acid derivatives or via aldol condensations of benzaldehyde and suitable enolates in few steps.These racemates were resolved with lipases from Candida cylindracea (CC) and Pseudomonas fluorescens (P) and the obtained products were hydrogenated to 3-phenylserines and -isoserines.The influence of the acyl group in the enzymatic resolution of erythro-3-azido-2-acyloxy-3-phenylpropionic esters was investigated.