13059-60-4 Usage
Uses
Glycylglycine is a derivative of Glycine (G615990), a non-essential amino acid that enhances N-methyl-D-aspartate (NMDA) receptor mediated synaptic potentials in the neocortex of rats. Glycine is also being used as adjuvant therapy for the treatment of schizophrenia.
Purification Methods
Crystallise the salt twice from 95% EtOH. Single crystals are formed by slow evaporation of an aqueous solution. [Parthasarathy Acta Cryst (B) 25 509 1969, Mellon & Hoover J Am Chem Soc 73 3879 1951, Garfinkel & Edsall J Am Chem Soc 80 3818 1958, Beilstein 4 IV 2469.]
Check Digit Verification of cas no
The CAS Registry Mumber 13059-60-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,5 and 9 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 13059-60:
(7*1)+(6*3)+(5*0)+(4*5)+(3*9)+(2*6)+(1*0)=84
84 % 10 = 4
So 13059-60-4 is a valid CAS Registry Number.
InChI:InChI=1/C4H8N2O3.ClH/c5-1-3(7)6-2-4(8)9;/h1-2,5H2,(H,6,7)(H,8,9);1H
13059-60-4Relevant articles and documents
ETUDE D'UN SCHEMA DE SYNTHESE PEPTIDIQUE INTRAMOLECULAIRE A L'AIDE DE DERIVES DU PHOSPHORE TETRAEDRIQUE
Mulliez, M.
, p. 2027 - 2041 (2007/10/02)
A new scheme of repetitive and controlled peptide synthesis offers two advantages compared to the usual methods of synthesis: two steps only are used for the prolongation of a peptide chain with an amino-acid residue and the risk of racemisation is minimized.The two postulated steps are verified particularly by the rearrangement, in an alkaline alcoholic medium, of phosphordiamides 1 incorporating one amino-acid residue, leading to the formation of the peptide derivatives 6 and 8.The severe limitations of this method are discussed.
