130601-96-6

Basic information

• Product Name: (E)-1-methyl-2-phenylmethylenecyclopentanol
• Synonyms: (E)-1-methyl-2-phenylmethylenecyclopentanol
• CAS NO: 130601-96-6
• Molecular Weight: 188.269
• Mol File: 130601-96-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-1-methyl-2-phenylmethylenecyclopentanol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-methyl-2-phenylmethylenecyclopentanol(130601-96-6)
• EPA Substance Registry System: (E)-1-methyl-2-phenylmethylenecyclopentanol(130601-96-6)

Safety Data

• Hazardous Substances Data: 130601-96-6(Hazardous Substances Data)

Upstream product

• 190258-44-7 di-tert-butyl-{1-methyl-3-phenyl-1-[3-(tetrahydropyran-2-yloxy)propyl]prop-2-ynyloxy}silane 
• 173728-30-8 di-tert-butyl-<1-(3-iodopropyl)-1-methyl-3-phenylprop-2-ynyloxy>silane 
• 190258-40-3 3-Methyl-1-phenyl-6-<(tetrahydro-2H-pyran-2-yl)oxy>-1-hexyn-3-ol 
• 173728-34-2 (E)-1-di-tert-butyliodosilyloxy-1-methyl-2-phenylmethylenecyclopentane 
• 130602-10-7 7-phenyl-6-heptyn-2-one 

Relevant articles and documents

Stereoselective hydrogen transfer reactions of vinyl radicals: Cyclization of alkynyl iodides by unimolecular chain transfer from silicon hydrides

The cyclization of several substituted hexynyl and heptynyl iodides proceeds stereoselectively to give either E- or Z-exocyclic double bonds depending on the type of precursor and radical chain used, In UniMolecular Chain Transfer (UMCT) reactions, the intramolecular abstraction of hydrogen by the intermediate vinyl radical leads exclusively to the E-isomer while the traditional tin hydride method usually provides the Z-isomer with good selectivity.

Intramolecular reductive cyclization of aldehydes and ketones with alkynes promoted by samarium(II) iodide

Samarium(II) iodide mediated intramolecular reductive coupling of carbonyl groups and alkynes in the presence of HMPA and t-BuOH was successfully performed to provide cyclized products. Some cyclic compounds containing a heteroatom such as oxygen or nitrogen were also efficiently prepared by this coupling reaction.