130745-65-2

Basic information

• Product Name: Cyclohexanol, 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-, trans-
• CAS NO: 130745-65-2
• Molecular Formula: C22H30O2Si
• Molecular Weight: 354.565
• Mol File: 130745-65-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Cyclohexanol, 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanol, 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-, trans-(130745-65-2)
• EPA Substance Registry System: Cyclohexanol, 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-, trans-(130745-65-2)

Safety Data

• Hazardous Substances Data: 130745-65-2(Hazardous Substances Data)

Upstream product

• 130745-59-4 4-<(tert-Butyldiphenylsilyl)oxy>cyclohexanone 
• 556-48-9 1,4-Cyclohexanediol 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 874650-36-9 1-bromo-3-[cis-4-(tert-butyl-diphenylsilyloxy)-cyclohexyloxy]-4-chloro-benzene 

Relevant articles and documents

D-xylopyranosyl-phenyl-substituted cycles, medicaments containing such compounds, their use and process for their manufacture

D-Glucopyranosyl-phenyl-substituted cycles of general formula I wherein the groups R1 to R6, Z, Cy and R7a, R7b, R7c, R7d are defined as in claim 1, have an inhibiting effect on the sodium-dependent glucose cotransporter SGLT. The present invention also relates to pharmaceutical compositions for the treatment of metabolic disorders.

Generalization, Alteration, and Enhancement of the Stereoselectivity in the Cieplak-Mode Reductions of 4-Alkoxy(or Silyloxy)cyclohexanones

Reductions of 4-alkoxy(or silyloxy)cyclohexanones with LiAlH4, AlH(i-Bu)2, and Li(s-Bu)3BH afforded the correponding cis alcohols in 73-80percent selectivities.Similar reduction of 4-benzyloxy- and 4-t-butyldiphenylsilyloxy-cyclohexanones with AlH(i-Bu)2