1308257-54-6

Basic information

• Product Name: (S)-2-((S)-1-tert-butoxycarbonylethylamino)-3-(2',5'-dichlorobiphenyl-4-yl)propionic acid benzyl ester
• Synonyms: (S)-2-((S)-1-tert-butoxycarbonylethylamino)-3-(2',5'-dichlorobiphenyl-4-yl)propionic acid benzyl ester
• CAS NO: 1308257-54-6
• Molecular Weight: 528.475
• Mol File: 1308257-54-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-((S)-1-tert-butoxycarbonylethylamino)-3-(2',5'-dichlorobiphenyl-4-yl)propionic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((S)-1-tert-butoxycarbonylethylamino)-3-(2',5'-dichlorobiphenyl-4-yl)propionic acid benzyl ester(1308257-54-6)
• EPA Substance Registry System: (S)-2-((S)-1-tert-butoxycarbonylethylamino)-3-(2',5'-dichlorobiphenyl-4-yl)propionic acid benzyl ester(1308257-54-6)

Safety Data

• Hazardous Substances Data: 1308257-54-6(Hazardous Substances Data)

Upstream product

• 68166-83-6 D-lactic acid t-butyl ester 
• 102605-72-1 (R)-2-trifluoromethanesulfonyloxypropionic acid tert-butyl ester 
• 1308257-53-5 (S)-2-amino-3-(2',5'-dichlorobiphenyl-4-yl)propionic acid benzyl ester hydrochloride 

Relevant articles and documents

METHOD OF TREATING CONTRAST-INDUCED NEPHROPATHY

The present invention provides the use of a neutral endopeptidase inhibitor, in the manufacture of a medicament for the treatment, amelioration and/or prevention of contrast-induced nephropathy. The invention also relates to the use of a compound of Formula I: wherein R1, R2, R3, R5, X, A3, B1, s and n are defined herein, for the treatment, amelioration and/or prevention of contrast-induced nephropathy. The present invention further provides a combination of pharmacologically active agents for use in the treatment, amelioration and/or prevention of contrast-induced nephropathy.