130916-46-0

Basic information

• Product Name: N-Bromoacetyl-2-chloro-5-nitroaniline
• Synonyms: N-Bromoacetyl-2-chloro-5-nitroaniline
• CAS NO: 130916-46-0
• Molecular Weight: 293.504
• Mol File: 130916-46-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-Bromoacetyl-2-chloro-5-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-Bromoacetyl-2-chloro-5-nitroaniline(130916-46-0)
• EPA Substance Registry System: N-Bromoacetyl-2-chloro-5-nitroaniline(130916-46-0)

Safety Data

• Hazardous Substances Data: 130916-46-0(Hazardous Substances Data)

Upstream product

• 22118-09-8 2-bromoacetyl chloride 
• 6283-25-6 H₂NC₆H₃(Cl)NO₂ 

Downstream Products

• 130916-52-8 N-(2-Chloro-5-nitrophenyl)-N-methyl-2-<(2-cyanophenyl)oxy>acetamide 
• 130940-76-0 N-(2-Chloro-5-nitrophenyl)-N-methyl-3-amino-2-benzofurancarboxamide 
• 130916-55-1 N-(2-Chloro-5-nitrophenyl)-3-amino-2-benzofurancarboxamide 
• 130916-49-3 N-(2-chloro-5-nitrophenyl)-2-<(2-cyanophenyl)oxy>acetamide 

Relevant articles and documents

Synthesis of New Arylbenzofurodiazepin-6-ones

Two new tetracyclic structures, containing the diazepine ring, were synthesized: 5,6-dihydro-12H-benzofurobenzodiazepin-6-one and 5,6-dihydro-12H-benzofuropyridodiazepin-6-one.Thus N-(2-haloaryl)-2-acetamides were cyclized to the corresponding N-(2-haloaryl)-3-amino-2-benzofurancarboxamides and then, through the formation of the central diazepine ring, to the title compounds.Formation of the diazepine ring took place only when an electron-withdrawing group was present in the molecule to facilitate the nucleophilic attack of an amine in the benzofuran intermediate.