1309261-80-0

Basic information

• Product Name: C₂₁H₁₄N₄O₂S
• CAS NO: 1309261-80-0
• Molecular Weight: 386.434
• Mol File: 1309261-80-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₄N₄O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₄N₄O₂S(1309261-80-0)
• EPA Substance Registry System: C₂₁H₁₄N₄O₂S(1309261-80-0)

Safety Data

• Hazardous Substances Data: 1309261-80-0(Hazardous Substances Data)

Upstream product

• 1520-26-9 2-hydroxyphenylthiourea 
• 7471-03-6 2-amino-4-hydroxybenzothiazole 
• 98-88-4 benzoyl chloride 
• 118-92-3 anthranilic acid 

Relevant articles and documents

QSAR modeling of synthesized 3-(1,3-benzothiazol-2-yl) 2-phenyl quinazolin-4(3H)-ones as potent antibacterial agents

Present communication elicits the designing and synthesis of 3-(1,3-benzothiazol-2-yl) 2-phenyl quinazolin-4(3H)-ones as potential antibacterial agents. A number of substituted 2-amino benzothiazoles, 2-amino-5-[(E)-phenyl diazenyl] benzoic acid, and 2-phenyl-4H benzo[d] [1,3] oxazin-4-one were synthesized as the precursor substrates. The compounds were synthesized in excellent yields and the structures were corroborated on the basis of IR, 1H NMR, Mass, and elemental analysis data. These compounds were screened in vitro for their antibacterial activity against a representative panel of Gram positive and Gram negative bacteria and models were generated through quantitative structure-activity relationship (QSAR).The activity contributions due to structural and substituent effects were determined using sequential regression procedure. The antimicrobial assay data show that the synthesized compounds are found to manifest profound antimicrobial activity. Springer Science+Business Media, LLC 2011.