1309476-89-8

Basic information

• Product Name: (4-(3-chloropropoxy)phenyl)(5-amino-2-butylbenzofuran-3-yl)methanone
• Synonyms: (4-(3-chloropropoxy)phenyl)(5-amino-2-butylbenzofuran-3-yl)methanone
• CAS NO: 1309476-89-8
• Molecular Weight: 385.89
• Mol File: 1309476-89-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4-(3-chloropropoxy)phenyl)(5-amino-2-butylbenzofuran-3-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(3-chloropropoxy)phenyl)(5-amino-2-butylbenzofuran-3-yl)methanone(1309476-89-8)
• EPA Substance Registry System: (4-(3-chloropropoxy)phenyl)(5-amino-2-butylbenzofuran-3-yl)methanone(1309476-89-8)

Safety Data

• Hazardous Substances Data: 1309476-89-8(Hazardous Substances Data)

Upstream product

• 133238-87-6 2-(n-butyl)-5-nitrobenzofuran 
• 100-07-2 4-methoxy-benzoyl chloride 
• 141627-42-1 (2-butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone 
• 1310430-03-5 (4-(3-chloropropoxy)phenyl)(2-butyl-5-nitrobenzofuran-3-yl)methanone 
• 141645-16-1 2-n-butyl-3-(4-hydroxybenzoyl)-5-nitrobenzofuran 

Downstream Products

• 1310430-05-7 N-(2-butyl-3-(4-(3-chloropropoxy)benzoyl)benzofuran-5-yl)methanesulfonamide 
• 141626-36-0 dronedarone 
• 141625-93-6 dronedarone hydrochloride 

Relevant articles and documents

A Novel and efficient synthesis of dronedarone hydrochloride, an antiarrhythmic drug substance

A novel and efficient synthesis of dronedarone hydrochloride starting from 2-n-butyl-5-nitrobenzofuran by employing mild and selective reaction conditions is described. The synthetic approach is operationally simple and suitable for industrial application.