131266-15-4

Basic information

• Product Name: 1,3-Propanediol, 2-[2-(2-amino-7H-purin-7-yl)ethyl]-, diacetate (ester)
• CAS NO: 131266-15-4
• Molecular Formula: C14H19N5O4
• Molecular Weight: 321.336
• Mol File: 131266-15-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3-Propanediol, 2-[2-(2-amino-7H-purin-7-yl)ethyl]-, diacetate (ester)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Propanediol, 2-[2-(2-amino-7H-purin-7-yl)ethyl]-, diacetate (ester)(131266-15-4)
• EPA Substance Registry System: 1,3-Propanediol, 2-[2-(2-amino-7H-purin-7-yl)ethyl]-, diacetate (ester)(131266-15-4)

Safety Data

• Hazardous Substances Data: 131266-15-4(Hazardous Substances Data)

Usage

Functionality

Used as an intermediate in the synthesis of pharmaceuticals and other organic compounds

Structure

A diacetate ester of a 1,3-Propanediol derivative containing a purinyl moiety

Biological Activity

Has potential biological activity and is used in research and development of new drugs

Safety Precautions

Important to handle with care and follow safety protocols due to potential health hazards

Applications

Widely used in the pharmaceutical industry for the development of new drugs

Molecular Weight

330.31 g/mol

Appearance

Colorless to white crystalline solid

Solubility

Soluble in organic solvents like methanol, ethanol, and dimethyl sulfoxide (DMSO)

Stability

Stable under normal temperature and pressure, but sensitive to moisture and light

Storage

Should be stored in a cool, dry, and well-closed container, protected from light and moisture

Hazardous Classification

Classified as a hazardous substance due to its potential health risks

Regulatory Information

Follow local and international regulations for handling, storage, and disposal of hazardous chemicals

Disposal

Dispose of in accordance with local regulations and guidelines for hazardous waste management

Upstream product

• 127047-77-2 4-acetoxy-3-(acetoxymethyl)-1-iodobutane 
• 452-06-2 9H-purin-2-amine 
• 126589-82-0 2-Acetoxymethyl-4-bromobut-1-yl acetate 

Relevant articles and documents

PROCESS FOR PREPARING 9-[4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]-2-AMINOPURINE

Disclosed is a process for preparing 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine (called Famciclovir), a drug of purine derivatives having antiviral activity. This process comprises reacting 2-aminopurine with 2-acetoxymethyl-4-bromobut-1-yl-acetate in the presence of thallium (I) ethoxide to give the desired compound. According to this process, the desired compound can be prepared in very high selectivity and purity under mild reaction conditions.