13129-60-7

Basic information

• Product Name: 2-[(5-Chloropentyl)oxy]tetrahydro-2H-pyran
• Synonyms: 2-[(5-Chloropentyl)oxy]tetrahydro-2H-pyran
• CAS NO: 13129-60-7
• Molecular Formula: C₁₀H₁₉ClO₂
• Molecular Weight: 206.71266
• Mol File: 13129-60-7.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 285.3 °C at 760 mmHg
• Flash Point: 95.7 °C
• Appearance: /
• Density: 1.03 g/cm³
• Vapor Pressure: 0.00485mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: 2-[(5-Chloropentyl)oxy]tetrahydro-2H-pyran(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(5-Chloropentyl)oxy]tetrahydro-2H-pyran(13129-60-7)
• EPA Substance Registry System: 2-[(5-Chloropentyl)oxy]tetrahydro-2H-pyran(13129-60-7)

Safety Data

• Hazardous Substances Data: 13129-60-7(Hazardous Substances Data)

Usage

Synonyms

CPTHP

Chemical Class

Pyran derivatives

Physical State

Colorless, flammable liquid

Odor

Faint

Solubility

Insoluble in water, soluble in organic solvents

Uses

Intermediate in the synthesis of pharmaceuticals and agrochemicals, solvent, reagent in organic synthesis

Health Hazards

Skin and eye irritation

Safety Measures

Handle and store with appropriate safety measures

Volatility

Low

Acute Toxicity

Low

InChI:InChI=1/C10H19ClO2/c11-7-3-1-4-8-12-10-6-2-5-9-13-10/h10H,1-9H2

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 5259-98-3 5-chloropentan-1-ol 
• 20395-28-2 5-chloropentyl acetate 
• 14273-86-0 methyl 5-chloropentanoate 

Downstream Products

• 31502-19-9 (E)-6-nonen-1-ol 
• 54364-62-4 (7E,9Z)-7,9-dodecadien-1-yl acetate 
• 14113-05-4 (E)-10-hydroxy-dec-2-enoic acid 
• 171087-54-0 (8E,11Z)-1-bromoheptadeca-8,11-diene 
• 20221-27-6 methyl (9E,12Z)-octadeca-9,12-dienoate 
• 37011-86-2 tetrahydro-2-(6-heptynyloxy)-2H-pyran 
• 173542-25-1 3-<5-(tetrahydro-2-pyranyloxy)pentyl>-2-cyclohexen-1-one 
• 100548-11-6 [1-Methoxy-1-phenylsulfanyl-6-(tetrahydro-pyran-2-yloxy)-hexyl]-trimethyl-silane 
• 100548-21-8 tert-Butyl-[1-methoxy-1-phenylsulfanyl-6-(tetrahydro-pyran-2-yloxy)-hexyl]-dimethyl-silane 

Relevant articles and documents

A NOVEL SYNTHESIS OF ROYAL JELLY ACIDS AND QUEEN SUBSTANCE BY THE FIVE CARBON HOMOLOGATION USING β-VINYL-β-PROPIOLACTONE

10-Hydroxy-(E)-2-decenoic acid, (E)-2-decenedioic acid (Royal jelly acids), and 9-oxo-(E)-2-decenoic acid (queen substance) were synthesized via 10-hydroxy-3-decenoic acid and 9,9-ethylenedioxy-3-decenoic acid, respectively, prepared easily by the regioselective ring-opening reaction of β-vinyl-β-propiolactone with Grignard reagents in the presence of copper(I) catalyst.

Nitroimidazoles and hypoxia imaging: Synthesis of three Technetium-99m complexes bearing a nitroimidazole group: Biological results

Several Tc-99m complexes were synthesized, substituted with a nitroimidazole group, in order to visualize hypoxic tissues. The complexes were tested on rats (isolated hearts) and showed no significant uptake under hypoxic conditions. (C) 2000 Elsevier Science Ltd.

POLYMERIZABLE COMPOUND AND OPTICAL ANISOTROPIC BODY

To provide a polymerizable compound giving such properties when added to a solution comprising a polymerizable composition that the resultant polymerizable composition has high storage stability and can induce a liquid crystal phase alignment in a short t

POLYMERIZABLE COMPOUND AND OPTICAL ISOMER

The present invention provides a polymerizable compound having high storage stability without causing crystal precipitation when added to a polymerizable composition. The present invention also provides a polymerizable composition containing the compound. When the filmy polymer produced through polymerization of the polymerizable composition is irradiated with UV light, it hardly discolors or peels from substrate. Further, the present invention provides a polymer produced through polymerization of the polymerizable composition and an optically anisotropic body using the polymer.

Donepezil–melatonin hybrids as butyrylcholinesterase inhibitors: Improving binding affinity through varying mode of linking fragments

Hybrid inhibitors of acetyl- and butyrylcholinesterase are compounds that combine structural motifs of two different classical inhibitors, leading to a dual binding ligand. A rapidly growing collection of those compounds involves a wide diversity of structural motifs, but the way of linking two active fragments and its impact on the affinity toward cholinesterases usually remains beyond the extent of investigation. We present hereby a detailed analysis of this aspect using melatonin–donepezil hybrids. A new series of compounds, in which two fragments are connected using a carbamate linker, exhibits excellent activity and selectivity toward butyrylcholinesterase.