1313028-09-9Relevant articles and documents
Total Synthesis and Structural Revision of Mangrolide D
Hattori, Hiromu,Hoff, Lukas V.,Gademann, Karl
, p. 3456 - 3459 (2019)
The unique 18-membered macrocyclic natural product mangrolide D was prepared in totally synthetic form. Key steps feature an Au-catalyzed glycosylation, aza-Michael addition, and LaLi3tris(binaphthoxide) catalyzed epoxidation. Detailed analysis
Green preparation method of 3-hydroxy isoindole-1-one compounds
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, (2020/01/03)
The invention discloses a green preparation method of 3-hydroxy isoindole-1-one compounds, and belongs to the technical field of organic synthesis. The method comprises the following steps: adopting 2-alkynyl benzamide as a reaction substrate, adding a br
PhI(OCOCF3)2-Mediated Cyclization of o -(1-Alkynyl)benzamides: Metal-Free Synthesis of 3-Hydroxy-2,3-dihydroisoquinoline-1,4-dione
Yang, Chao,Zhang, Xiang,Zhang-Negrerie, Daisy,Du, Yunfei,Zhao, Kang
, p. 5320 - 5328 (2015/05/27)
The synthesis of an undocumented skeleton of 3-hydroxy-2,3-dihydroisoquinoline-1,4-diones has been discovered and reported. The reaction consists of an intramolecular cyclization of o-(1-alkynyl)benzamides in MeCN/H2O, mediated by metal-free, h