1313843-56-9

Basic information

• Product Name: 2-(4-chloro-2-nitrophenyl)-1-(4-chlorophenyl)ethanol
• CAS NO: 1313843-56-9
• Molecular Weight: 312.152
• Mol File: 1313843-56-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-chloro-2-nitrophenyl)-1-(4-chlorophenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chloro-2-nitrophenyl)-1-(4-chlorophenyl)ethanol(1313843-56-9)
• EPA Substance Registry System: 2-(4-chloro-2-nitrophenyl)-1-(4-chlorophenyl)ethanol(1313843-56-9)

Safety Data

• Hazardous Substances Data: 1313843-56-9(Hazardous Substances Data)

Upstream product

• 89-59-8 4-chloro-2-nitrotoluene 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 1313843-82-1 8-chloro-4-(4-chlorophenyl)-4,5-dihydro-2-phenyl-3,1-benzoxazepine 
• 1313843-83-2 8-chloro-4-(4-chlorophenyl)-2-ethyl-4,5-dihydro-3,1-benzoxazepine 
• 1313843-59-2 2-(2-amino-4-chlorophenyl)-1-(4-chlorophenyl)ethanol 

Relevant articles and documents

One-pot synthesis of 2-substituted 4-aryl-4,5-dihydro-3,1-benzoxazepines from 2-(2-Aminophenyl)-1-arylethanols via dehydration of the corresponding amides

An efficient method for the preparation of 2-substituted 4-aryl-4,5-dihydro-3,1-benzoxazepine derivatives under mild conditions has been developed. The reaction of 2-(2-aminophenyl)ethanols 1 with acid chlorides in the presence of excess Et3N in THF at room temperature gave the corresponding N-acylated intermediates 2, which were dehydrated by treatment with POCl3 to give 2-substituted 4-aryl-4,5-dihydro-3,1- benzoxazepines 3 in a one-pot reaction.