1313870-24-4Relevant articles and documents
Enantioselective N-Heterocyclic Carbene Catalysis via Acyl Azolium without Exogenous Oxidants
Breugst, Martin,Cao, Jing,Gillard, Rachel,Jahanbakhsh, Azar,Lupton, David W.
, p. 11791 - 11796 (2020)
An approach to the α,β-unsaturated acyl azolium has been developed that exploits N-heterocyclic carbenes (NHCs) and acyl fluorides, without additional oxidants, bases, or preactivated pro-nucleophiles. These conditions have been applied in four classes of
Enantioselective synthesis of fused dihydropyranones via squaramide-catalyzed Michael addition/lactonization cascade reaction
Xian, Jialing,Chen, Lin,Ye, Ling,Sun, Yin,Shi, Zhichuan,Zhao, Zhigang,Li, Xuefeng
, p. 2350 - 2356 (2019/03/17)
A highly enantioselective (49–99% ee) Michael addition/lactonization cascade process has been developed to construct 3,4-dihydropyran-2-one in the presence of a bifunctional squaramide. Various α,β-unsaturated N-acyl heterocycles were well tolerated and afforded 3,4-dihydropyran-2-ones in moderate to excellent isolated yields (50–99%). Both cyclic and acyclic β-diketones functioned as appropriate donors. The resulting 3,4-dihydropyran-2-ones could be readily converted into oxadecalinones.
Polyhalides as Efficient and Mild Oxidants for Oxidative Carbene Organocatalysis by Radical Processes
Wu, Xingxing,Zhang, Yuexia,Wang, Yuhuang,Ke, Jie,Jeret, Martin,Reddi, Rambabu N.,Yang, Song,Song, Bao-An,Chi, Yonggui Robin
supporting information, p. 2942 - 2946 (2017/03/13)
Simple and inexpensive polyhalides (CCl4 and C2Cl6) have been found to be effective and versatile oxidants in removing electrons from Breslow intermediates under N-heterocyclic carbene (NHC) catalysis. This oxidative react
