13142-09-1 Usage
General Description
1-(4-bromophenyl)-3-(3-chlorophenyl)urea is a chemical compound that consists of a urea molecule with a 4-bromophenyl group and a 3-chlorophenyl group attached to it. 1-(4-bromophenyl)-3-(3-chlorophenyl)urea is a synthetic organic compound with potential applications in pharmaceuticals and agrochemicals. It may exhibit various biological activities and can be used as a building block for the synthesis of other more complex molecules. The presence of bromine and chlorine atoms in the compound may confer specific chemical and physical properties that make it suitable for different applications in the chemical industry. Additionally, the compound's structure and properties may make it interesting for further research and development in the field of medicinal chemistry and organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 13142-09-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,4 and 2 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 13142-09:
(7*1)+(6*3)+(5*1)+(4*4)+(3*2)+(2*0)+(1*9)=61
61 % 10 = 1
So 13142-09-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H10BrClN2O/c14-9-4-6-11(7-5-9)16-13(18)17-12-3-1-2-10(15)8-12/h1-8H,(H2,16,17,18)
13142-09-1Relevant articles and documents
Synthesis, in vitro urease inhibitory activity, and molecular docking studies of thiourea and urea derivatives
Bano, Bilquees,Kanwal,Khan, Khalid Mohammed,Lodhi, Arif,Salar, Uzma,Begum, Farida,Ali, Muhammad,Taha, Muhammad,Perveen, Shahnaz
, p. 129 - 144 (2018/06/20)
The current study deals with the synthesis of urea and thiourea derivatives 1–37 which were characterized by various spectroscopic techniques including FAB-MS, 1H-, and 13C NMR. The synthetic compounds were subjected to urease inhibitory activity and compounds exhibited good to moderate urease inhibitory activity having IC50 values in range of 10.11–69.80 μM. Compound 1 (IC50 = 10.11 ± 0.11 μM) was found to be most active and even better as compared to the standard acetohydroxamic acid (IC50 = 27.0 ± 0.5 μM). A limited structure–activity relationship (SAR) was established and the compounds were also subjected to docking studies to confirm the binding interactions of ligands (compounds) with the active site of enzyme.