1314247-99-8Relevant articles and documents
Palladium-catalyzed synthesis of indoles via ammonia cross-coupling-alkyne cyclization
Alsabeh, Pamela G.,Lundgren, Rylan J.,Longobardi, Lauren E.,Stradiotto, Mark
supporting information; experimental part, p. 6936 - 6938 (2011/08/06)
The synthesis of indoles via the metal-catalyzed cross-coupling of ammonia is reported for the first time; the developed protocol also allows for the unprecedented use of methylamine or hydrazine as coupling partners. These Pd/Josiphos-catalyzed reactions proceed under relatively mild conditions for a range of 2-alkynylbromoarenes.