13143-42-5

Basic information

• Product Name: 1-(4-methylphenyl)-3-propylurea
• Synonyms: 1-(4-Methylphenyl)-3-propylurea; urea, N-(4-methylphenyl)-N'-propyl-
• CAS NO: 13143-42-5
• Molecular Formula: C₁₁H₁₆N₂O
• Molecular Weight: 192.2575
• Mol File: 13143-42-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 285.8°C at 760 mmHg
• Flash Point: 107.4°C
• Density: 1.064g/cm³
• Vapor Pressure: 0.00274mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: 1-(4-methylphenyl)-3-propylurea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methylphenyl)-3-propylurea(13143-42-5)
• EPA Substance Registry System: 1-(4-methylphenyl)-3-propylurea(13143-42-5)

Safety Data

• Hazardous Substances Data: 13143-42-5(Hazardous Substances Data)

Usage

General Description

1-(4-methylphenyl)-3-propylurea is a chemical compound with the molecular formula C12H17N3O. It is an urea derivative with a p-propylphenyl substituent at the 3-position and a methyl group at the 1-position. This chemical has potential applications in the pharmaceutical and agricultural industries due to its reported anti-inflammatory and anti-cancer properties. It may also be used as a research tool in the study of urea derivatives and their biological activities. However, further research is needed to fully understand the potential uses and effects of 1-(4-methylphenyl)-3-propylurea.

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Relevant articles and documents

A Fe3O4?SiO2/Schiff Base/Pd Complex as an Efficient Heterogeneous and Recyclable Nanocatalyst for One-Pot Domino Synthesis of Carbamates and Unsymmetrical Ureas

A palladium-catalyzed domino method for the direct synthesis of carbamates and ureas has been developed by using readily available and economical starting materials (aryl halide, carbon monoxide, sodium azide, amines and alcohols) in a one-pot approach. The domino process underwent carbonylation, Curtius rearrangement, and nucleophilic addition. This protocol provides a step-economical and highly efficient reaction to access the wide range of valuable carbamates, symmetrical and unsymmetrical ureas with high yields under remarkable mild reaction conditions that are important factors in pharmaceutical science, biochemistry and agricultural industries. Furthermore, the magnetically recoverable nanocatalyst (Fe3O4?SiO2/Pd(II)) can be conveniently and swiftly recycled using external magnet and reused at least for seven times without noticeable loss of its catalytic activity.