131436-64-1Relevant articles and documents
A highly specific aldose reductase inhibitor, ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate, and its congeners
Mylari,Beyer,Siegel
, p. 1011 - 1018 (2007/10/02)
Ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate (1, EBPC) is a potent and specific inhibitor of aldose reductase. It was >4000X more potent in its inhibition of rat lens aldose reductase than the closely related rat or pig kidney aldehyde reductas