1314978-36-3 Usage
Description
5-Chloropyridazin-3-aMine is an organic compound that serves as a key intermediate in the synthesis of various chemical compounds. It is characterized by the presence of a chloro substituent at the 5-position and an amine group at the 3-position of the pyridazine ring. This unique structure endows it with versatile reactivity and potential applications in different fields.
Uses
Used in Pharmaceutical Industry:
5-Chloropyridazin-3-aMine is used as an intermediate in the preparation of aminopyrazines, which are novel and potent Nav1.7 antagonists. These Nav1.7 antagonists have potential therapeutic applications in the treatment of pain, as they target the voltage-gated sodium channel Nav1.7, which plays a crucial role in the transmission of pain signals in the peripheral nervous system.
Check Digit Verification of cas no
The CAS Registry Mumber 1314978-36-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,4,9,7 and 8 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1314978-36:
(9*1)+(8*3)+(7*1)+(6*4)+(5*9)+(4*7)+(3*8)+(2*3)+(1*6)=173
173 % 10 = 3
So 1314978-36-3 is a valid CAS Registry Number.
1314978-36-3Relevant articles and documents
ANTHELMINTIC HETEROCYCLIC COMPOUNDS
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Page/Page column 95; 137-139, (2021/12/08)
This invention provides for compounds of the formula (I): wherein the variables are defined herein, or salt thereof, compositions comprising these compounds, and method for the treatment, control or prevention of a parasitic infestation or infection in an animal in need thereof by administering an effective amount of these compounds to said animal.
CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS
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Paragraph 0532, (2019/07/13)
The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula (I); where A1, A2, G, R1, R2, R3, R4, and W are described herein.
SUBSTITUTED IMIDAZOPYRIDAZINES AND BENZIMIDAZOLES AS INHIBITORS OF FGFR3
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Page/Page column 34, (2012/07/13)
The present invention relates to substituted imidazopyridazines and substituted benzimidazoles, as well as pharmaceutical compositions comprising the same, which are FGFR3 inhibitors useful in the treatment of cancer and other diseases.
