1315368-00-3 Usage
Chemical structure
A pyrrolidine ring with a benzyl group and two trifluoromethyl groups attached to it.
Usage
Commonly used as a building block in the synthesis of various pharmaceutical compounds and agrochemicals.
Applications
Has potential applications in medicinal chemistry due to its ability to interact with biological targets.
Field of interest
Of interest in the field of organic chemistry for its unique structure and reactivity.
Fluorinated pharmaceuticals
The trifluoromethyl groups present in this compound make it valuable for the development of fluorinated pharmaceuticals.
Enhancement of biological activity
Fluorine is known to enhance the biological activity of drug molecules.
Metabolic stability
Fluorine is known to improve the metabolic stability of drug molecules.
Please note that this list is based on the information provided in the material and may not be exhaustive.
Check Digit Verification of cas no
The CAS Registry Mumber 1315368-00-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,5,3,6 and 8 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1315368-00:
(9*1)+(8*3)+(7*1)+(6*5)+(5*3)+(4*6)+(3*8)+(2*0)+(1*0)=133
133 % 10 = 3
So 1315368-00-3 is a valid CAS Registry Number.
1315368-00-3Relevant articles and documents
Synthesis and characterization of β-trifluoromethyl-substituted pyrrolidines
Yarmolchuk, Vladimir S.,Shishkin, Oleg V.,Starova, Viktoriia S.,Zaporozhets, Olga A.,Kravchuk, Olga,Zozulya, Sergey,Komarov, Igor V.,Mykhailiuk, Pavel K.
, p. 3086 - 3093 (2013)
A practical synthetic approach to the construction of a library of three isomeric/homologous β-trifluoromethyl-substituted pyrrolidines is disclosed. All products were prepared in multigram quantities from a common precursor. The key synthetic step was a [3+2] cycloaddition reaction. The influence of the trifluoromethyl group on the physicochemical characteristics of the pyrrolidine fragment was studied. Three β-(trifluoromethyl)ated pyrrolidines have been synthesized on multigram scales. The influence of the CF3 group on the physicochemical properties of the pyrrolidine fragment has been studied. Copyright
