131575-71-8

Basic information

• Product Name: 1-(3,4-dimethoxyphenyl)-2-phenylsulphonylethyne
• Synonyms: 1-(3,4-dimethoxyphenyl)-2-phenylsulphonylethyne
• CAS NO: 131575-71-8
• Molecular Weight: 302.351
• Mol File: 131575-71-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3,4-dimethoxyphenyl)-2-phenylsulphonylethyne(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-dimethoxyphenyl)-2-phenylsulphonylethyne(131575-71-8)
• EPA Substance Registry System: 1-(3,4-dimethoxyphenyl)-2-phenylsulphonylethyne(131575-71-8)

Safety Data

• Hazardous Substances Data: 131575-71-8(Hazardous Substances Data)

Upstream product

• 882-33-7 diphenyldisulfane 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 118199-01-2 2,2-dibromo-1-(3,4-dimethoxyphenyl)ethene 
• 4302-52-7 4-ethynylveratrole 
• 131575-69-4 1-bromo-1-(3,4-dimethoxyphenyl)-2-phenylsulphonylethene 

Downstream Products

• 131575-74-1 (2S,3R)-2-[(E)-2-Benzenesulfonyl-1-(3,4-dimethoxy-phenyl)-vinyloxymethyl]-3-phenyl-oxirane 
• 131575-73-0 (2S,3R)-2-[(Z)-1-Benzenesulfonyl-2-(3,4-dimethoxy-phenyl)-vinyloxymethyl]-3-phenyl-oxirane 
• 131576-00-6 (2S,3S,4R,αS)-2-(3,4-dimethoxyphenyl)-3-phenylsulphonyl-4-(α-phenylsulphonylmethoxybenzyl)tetrahydrofuran 
• 131575-85-4 (4R,αS)-2-(3,4-dimethoxyphenyl)-3-phenylsulphonyl-4-(α-phenylsulphonylmethoxybenzyl)-4,5-dihydrofuran 
• 131575-99-0 (2S,3S,4R,αS)-2-(3,4-dimethoxyphenyl)-3-phenylsulphonyl-4-(α-phenylthiomethoxybenzyl)tetrahydrofuran 
• 131575-84-3 (4R,αS)-2-(3,4-dimethoxyphenyl)-3-phenylsulphonyl-4-(α-phenylthiomethoxybenzyl)-4,5-dihydrofuran 
• 131575-98-9 (2S,3S,4R,αS)-2-(3,4-dimethoxyphenyl)-3-phenylsulphonyl-4-(α-methylsulphonylmethoxybenzyl)tetrahydrofuran 
• 131575-81-0 (4R,αS)-2-(3,4-dimethoxyphenyl)-4-(α-dimethoxymethoxybenzyl)-3-phenylsulphonyl-4,5-dihydrofuran 
• 131575-95-6 (2S,3S,4R,αS)-2-(3,4-dimethoxyphenyl)-3-phenylsulphonyl-4-(α-ethoxycarbonyloxybenzyl)tetrahydrofuran 
• 131575-79-6 (4R,αS)-2-(3,4-dimethoxyphenyl)-4-(α-ethoxycarbonyloxybenzyl)-3-phenylsulphonyl-4,5-dihydrofuran 
• 131575-97-8 (2S,3S,4R,αS)-2-(3,4-dimethoxyphenyl)-3-phenylsulphonyl-4-(α-methylthiomethoxybenzyl)tetrahydrofuran 
• 131575-96-7 (2S,3S,4R,αS)-2-(3,4-dimethoxyphenyl)-3-phenylsulphonyl-4-(α-methoxymethyloxybenzyl)tetrahydrofuran 
• 131575-82-1 (4R,αS)-2-(3,4-dimethoxyphenyl)-4-(α-methylthiomethoxybenzyl)-3-phenylsulphonyl-4,5-dihydrofuran 
• 131575-80-9 (4R,αS)-2-(3,4-dimethoxyphenyl)-4-(α-methoxymethoxybenzyl)-3-phenylsulphonyl-4,5-dihydrofuran 

Relevant articles and documents

Copper-catalyzed regioselective synthesis of (E)-β-fluorovinyl sulfones

Organofluorine compounds are finding increasing application in a variety of fields such as pharmaceutical, agrochemical, and material sciences. However, given the scarcity of fluorine-containing natural products, advancement in this area depends almost entirely on the development of new synthetic methodologies. In this article, we present the synthesis of a series of previously undescribed (E)-β-fluorovinyl sulfones via a simple copper-catalyzed addition of hydrogen fluoride to alkynyl sulfone starting materials in varying yields and E/Z selectivities. The hydrogenation of these products was also explored and compared with the hydrogenation of the related Z isomers. These new products may find interesting applications, given the versatility of vinyl sulfones in chemical synthesis and the unique properties of vinyl fluorides in biological settings.