13159-73-4

Basic information

• Product Name: N-(2-Hydroxybenzyl)-4-nitroaniline
• Synonyms: N-(2-Hydroxybenzyl)-4-nitroaniline;α-(p-Nitroanilino)-o-cresol
• CAS NO: 13159-73-4
• Molecular Formula: C₁₃H₁₂N₂O₃
• Molecular Weight: 244.25
• Mol File: 13159-73-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 444.3°C at 760 mmHg
• Flash Point: 222.5°C
• Appearance: /
• Density: 1.357g/cm³
• Vapor Pressure: 1.65E-08mmHg at 25°C
• Refractive Index: 1.69
• CAS DataBase Reference: N-(2-Hydroxybenzyl)-4-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Hydroxybenzyl)-4-nitroaniline(13159-73-4)
• EPA Substance Registry System: N-(2-Hydroxybenzyl)-4-nitroaniline(13159-73-4)

Safety Data

• Hazardous Substances Data: 13159-73-4(Hazardous Substances Data)

Usage

General Description

N-(2-Hydroxybenzyl)-4-nitroaniline is a chemical compound that consists of a 4-nitroaniline moiety attached to a benzyl group with a hydroxyl substituent at the ortho position. It is commonly used in organic synthesis and research as a starting material for the preparation of various organic compounds. N-(2-Hydroxybenzyl)-4-nitroaniline is also known for its potential use as a dye precursor due to its aromatic nature and ability to undergo various chemical reactions. Additionally, N-(2-Hydroxybenzyl)-4-nitroaniline has shown potential applications in the pharmaceutical industry, particularly in the development of novel drugs and pharmaceutical products. Overall, this chemical represents a versatile building block with potential applications in several fields, including organic synthesis, dye industry, and pharmaceutical research.

InChI:InChI=1/C13H12N2O3/c16-13-4-2-1-3-10(13)9-14-11-5-7-12(8-6-11)15(17)18/h1-8,14,16H,9H2

Upstream product

• 90-01-7 salicylic alcohol 
• 100-01-6 4-nitro-aniline 
• 90-02-8 salicylaldehyde 
• 788-25-0 2-{[(E)-4-Nitro-phenylimino]-methyl}-phenol 
• 89-95-2 2-methyl-benzyl alcohol 
• 788-25-0 2-((4-nitrophenylimino)methyl)phenol 

Downstream Products

• 70301-61-0 3-chloro-5-(4-nitro-phenyl)-5,6-dihydro-benzo[f]pyridazino[3,4-b][1,4]oxazepine 
• 99779-31-4 2-chloro-N-(2-hydroxybenzyl)-N-(4-nitrophenyl)acetamide 
• 139554-05-5 4'-[(2-Hydroxy-benzyl)-(4-nitro-phenyl)-amino]-1'-phenyl-2,3,4,5-tetrahydro-[1,3']bipyrrolyl-2',5'-dione 
• 139554-00-0 10-(4-Nitro-phenyl)-2-phenyl-9,10-dihydro-4-oxa-2,10-diaza-benzo[f]azulene-1,3-dione 

Relevant articles and documents

A simple method for the reduction of Schiff bases using biosynthesized nickel oxide nanoparticles

An innovative and simple approach for the reduction of aldimines to the corresponding secondary amines was described using biosynthesized nickel oxide nanoparticles as heterogeneous catalyst and ammonium formate as the hydrogen donor. This catalytic trans

Structure-activity relationship study of E6 as a novel necroptosis inducer

Necroptosis inducers represent a promising potential treatment for drug-resistant cancer. We herein describe the structure modification of E6, which was identified recently as a potent and selective necroptosis inducer. The studies described herein demonstrate for the first time that functionalized biphenyl derivatives possess necroptosis inducer activity. Furthermore, these studies have led to the identification of two promising compounds (5h and 5j) that can be used for further optimization studies as well as mechanism of action investigations.

Sodium borohydride on wet clay: Solvent-free reductive amination of carbonyl compounds using microwaves

A solvent-flee reductive amination of carbonyl compounds by wet montmorillonite K 10 clay supported sodium borohydride is described; microwave irradiation facilitates the procedure.