13182-96-2

Basic information

• Product Name: 1H-Imidazole-1-propanenitrile, 4-nitro-
• CAS NO: 13182-96-2
• Molecular Formula: C6H6N4O2
• Molecular Weight: 166.139
• Mol File: 13182-96-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole-1-propanenitrile, 4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole-1-propanenitrile, 4-nitro-(13182-96-2)
• EPA Substance Registry System: 1H-Imidazole-1-propanenitrile, 4-nitro-(13182-96-2)

Safety Data

• Hazardous Substances Data: 13182-96-2(Hazardous Substances Data)

Upstream product

• 2417-90-5 bromopropionitrile 
• 3034-38-6 1H-4⁽⁵⁾-nitroimidazole 
• 107-13-1 acrylonitrile 

Downstream Products

• 215099-39-1 1-(2-Cyanoethyl)-4-aminoimidazole 
• 3034-42-2 1-methyl-5-nitro-1H-imidazole 

Relevant articles and documents

Polystyrene-supported CuI-imidazole complex catalyst for aza-Michael reaction of imidazoles with α,β-unsaturated compounds

The polystyrene-supported CuI-imidazole complex catalyst was prepared and characterized by IR spectroscopy, elemental analysis, SEM/TEM and TG/DSC. The complex catalyst was globular with the size of 400-500 nm and showed a good thermal stability at high temperature. The immobilized Cu metal in the complex catalyst was about 0.85 mmol/g. By using the catalyst, aza-Michael reaction of imidazoles to α,β-unsaturated compounds was performed with good yields in 4-8 h. The catalyst showed an excellent recycling efficiency over five cycles without distinct leaching of metal from the polymer support.

Preparation and biological evaluation of 99mTc-N4IPA for single photon emission computerized tomography imaging of hypoxia in mouse tumor

In order to develop technetium-99m labeled nitroimidazole imaging agent for hypoxia in tumor, we have synthesized 99mTc-1-(4-nitroimidazole-yl)- propanhydroxyiminoamide, 99mTc-N4IPA complex, in high radiochemical purity and radiochem

Triethylammonium acetate (TEAA): A recyclable inexpensive ionic liquid promotes the chemoselective aza- and thia-Michael reactions

A new, highly efficient, inexpensive, recyclable, mild, convenient, and green protocol for chemoselective aza/thia-Michael addition reactions of amines/thiols to α,β-unsaturated compounds using triethylammonium acetate (TEAA) ionic liquid was developed. The catalyst can be recycled ten times and obviate the need for toxic and expensive catalysts.