13194-48-4 Usage
Description
Introduced in the 1960s, ethoprop is a nonsystemic
insecticide/nematicide. The mobility of ethoprop in soil
and its half-life are strongly dependent on soil organic
matter (21). It is not known to be carcinogenic and is
available as granules or emulsifiable concentrates.
Chemical Properties
Different sources of media describe the Chemical Properties of 13194-48-4 differently. You can refer to the following data:
1. Clear Colorless Oil
2. Ethoprophos is a pale yellow liquid.
Uses
Different sources of media describe the Uses of 13194-48-4 differently. You can refer to the following data:
1. Nonsystemic, nonfumigant nematocide and soil insecticide for control of insects in
ornamentals, potatoes, sweet potatoes, tomatoes, strawberries, bananas, pineapples, sugar
cane, turf and many other crops.
2. Ethoprophos is used to control plant parasitic nematodes and soil
insects.
3. Ethoprophos is an organophosphate non-systemic nematicide and soil insecticide. Ethoprophos is an acetylcholinesterase (AChE) inhibitor.
4. Insecticide; nematocide.
General Description
Ethorop is one of a family of organophosphorus pesticides. Mocap is combustible though Mocap may require some effort to ignite. Mocap is very toxic by skin absorption and inhalation. Mocap may or may not be water soluble.
Air & Water Reactions
Hydrolyzed in alkali.
Reactivity Profile
Organothiophosphates, such as Mocap, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Health Hazard
Mocap is extremely toxic; the probable oral lethal dose for humans is 5-50 mg/kg, or between 7 drops and 1 teaspoonful for a 150 lb. person. It is a cholinesterase inhibitor which affects the nervous system.
Fire Hazard
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Fire and runoff from fire control water may produce irritating or poisonous gases. Stable in water. Hydrolyzed in alkali.
Agricultural Uses
Nematicide, Insecticide: Ethoprop is used as a pre-plant soil application
to control wireworms and nematodes in potatoes, sugar
cane, sweet potatoes, and tobacco, with lesser usage
on corn (field and sweet), beans (lima and snap), cucumbers,
and cabbage. In addition, it is used to treat
pineapples, bananas, and plantains, as well as fieldgrown
ornamentals and non-bearing citrus trees, and
commercial turf. Roughly 60% of ethoprop is applied
to potatoes.
Trade name
AI3-27318?; CASWELL No. 434C?;
JOLT?[C]; MENAP?; MOBIL V-C 9-104?;
MOCAP?[C]; MOCAP 10G?[C]; PHOSETHOPROP?;
ROVOKIL?; V-C 9-104?[C]; V-C CHEMICAL V-C
9-104?[C]; VIRGINIA-CAROLINA VC 9-104?
Safety Profile
Poison by ingestion and
skin contact. A cholinesterase inhibitor type
of insecticide. When heated to
decomposition it emits very toxic fumes of
POx and SOx. See also PARATHION.
Potential Exposure
A potential danger to those involved
in the manufacture, formulation and application of this
nematocide and soil insecticide
Carcinogenicity
In a combined chronic feeding/
carcinogenicity study, when rats were fed diets with 0, 1, 10,
or 100 ppm ethoprop in the diet for 24 months (equivalent to
0, 0.041, 0.40, or 4.19 mg/kg/day (males); 0, 0.052, 0.51, or
5.12 mg/kg/day (females)), adrenal gland malignant pheochromocytomas
were increased in males and thyroid C-cell
carcinomas were increased slightly in males . When
ethoprop was administered in the diet to mice for 104 weeks
at 0, 0.2, 2.0, or 30 ppm (males: 0, 0.026, 0.254, or 3.96 mg/
kg/day; females: 0, 0.032, 0.318, or 4.9 mg/kg/day), survival
was unaffected at any dose level and no statistically significant
dose-related incidence of tumors were seen in males or
females.
Environmental Fate
Soil. The reported half-life in humus-containing soil (pH 4.5) and a sandy loam (pH
7.2–7.3) are 87 and 14–28 days, respectively (Hartley and Kidd, 1987). The rate of
degradation increased in soils that had been treated annually four times (Smelt et al., 1987).
Chemical/Physical. Emits toxic fumes of phosphorus and sulfur oxides when heated
to decomposition (Sax and Lewis, 1987).
Metabolic pathway
Ethoprophos is a soil-acting insecticide and nematicide which is generally
incorporated into the soil in the form of a granular formulation. Volatilisation
is a factor involved in the loss and movement of the compound in
the environment. The major route of degradation of ethoprophos in both
plants and mammals is via hydrolysis to give O-ethyl S-propyl phosphorothioate
through loss of propanethiol. Propanethiol has been shown
to react as a nucleophile to yield ethyl propyl sulfide through attack
on the phosphorus atom and dipropyl disulfide through attack on the
sulfur atom of ethoprophos. The sulfide metabolites are further metabolised
via oxidation to sulfoxides and sulfones. In mammals, an additional
important route of detoxification is through de-ethylation via glutathione-
S-alkyl transferase, a route common to many organophosphorus
insecticides.
Degradation
Ethoprophos is very stable in neutral and weakly acidic media but it is
hydrolysed rapidly in alkaline solutions (PM). The DT50 of ethoprophos in
0.05M NaOH solution at 25 °C was 35 min and the hydrolysis product
was identified as O-ethyl S-propyl phosphorothioate (2), indicating the
greater susceptibility of the P-S bond to hydrolysis over the P-O bond.
There was no measurable hydrolysis in 0.1M HCl after 1 hour (Menzer
et al., 1971). The route of the base-catalysed hydrolysis of ethoprophos is
shown in Scheme 1.
Incompatibilities
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, and epoxides. Strong oxidizers may
cause release of toxic phosphorus oxides. Organophosphates,
in the presence of strong reducing agents such as hydrides,
may form highly toxic and flammable phosphine gas. Keep
away from alkaline materials
Waste Disposal
In accordance with 40CFR
165 recommendations for the disposal of pesticides and
pesticide containers. Must be disposed properly by following package label directions or by contacting your local or
federal environmental control agency, or by contacting
your regional EPA office
Check Digit Verification of cas no
The CAS Registry Mumber 13194-48-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,9 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 13194-48:
(7*1)+(6*3)+(5*1)+(4*9)+(3*4)+(2*4)+(1*8)=94
94 % 10 = 4
So 13194-48-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3
13194-48-4Relevant articles and documents
Concentrates of organophosphorous insecticides
-
, (2008/06/13)
A low volatile organic compound co-solvent system is disclosed for preparing emulsion concentrates of low melting organophosphorous insecticides wherein the bioefficacy of the insecticide active is significantly enhanced. The co-solvent system comprises a water-soluble ethoxylated fatty acid/rosin acid-nonionic surfactant composition.
Halogen alkenyl azolyl microbicides
-
, (2008/06/13)
Novel halogenoalkenyl-azolyl derivatives of the formula STR1 in which R1 represents optionally substituted alkyl, optionally substituted alkenyl, optionally substituted cycloalkyl, optionally substituted aryl or represents optionally substituted heteroaryl, R2 represents alkyl, halogenoalkyl, 1-hydroxyalkyl, 2-hydroxyalkyl, 1-hydroxyhalogenalkyl, 1-alkenyl or 2-alkenyl, X1 represents fluorine, chlorine, bromine or iodine, X2 represents fluorine, chlorine, bromine or iodine, and Y represents nitrogen or a CH group, and addition products thereof with acids or metal salts are very active as microbicides in plant protection and in the protection of materials.
Polyhydroxy polymer delivery systems
-
, (2008/06/13)
A biologically active agent-containing composition is prepared by reacting an aqueous emulsion or dispersion of a suitable biologically active agent and an optional filler in an aqueous solution or gel of a polyhydroxy polymer and an inorganic salt, with a boric acid or boric acid derivative until an insolubilized matrix phase is formed having entrapped therein uniformly dispersed, discontinuous domains of said agent and an optional aqueous phase that can be separated from the matrix phase by decanting, filtration, or the like; the product is then dried and ground to the desired particle size. The composition is applied to the soil or plants where the biologically active agent is slow released for controlling pests.