132065-12-4Relevant articles and documents
New route to 4-aminocyclopent-2-en-1-ols: Synthesis and enantioselective rearrangement of 4-amino-substituted cyclopentene oxides
Barrett, Stephen,O'Brien, Peter,Steffens, H.Christian,Towers, Timothy D,Voith, Matthias
, p. 9633 - 9640 (2007/10/03)
A new route for the asymmetric synthesis of 4-aminocyclopent-2-en-1-ols (90% ee) for carbocyclic nucleoside analogue synthesis is described. The approach involves the stereoselective preparation of cis 4-amino-substituted cyclopentene oxides and subsequent chiral base-mediated rearrangement to the corresponding allylic alcohols. Full details on the synthesis and stereoselectivity of epoxidation of 4-amino-substituted cyclopentenes are presented. (C) 2000 Elsevier Science Ltd.
HYDROGEN BOND DIRECTED NITRILE OXIDE CYCLOADDITION REACTIONS OF ALLYLIC 2o-AMIDES
Curran, Dennis P.,Gothe, Scott A.,Choi, Sung-Mo
, p. 1371 - 1395 (2007/10/02)
The ability of allylic and homoallylic 2o-amides to direct nitrile oxide cycloaddition reactions has been studied.For N-cyclopentenyl amides, good regio- and stereochemical control are observed and mechanistic studies suggest that hydrogen bond
The synthesis of two 2'-deoxy carbocyclic purine nucleosides lacking the 5'-methylene
Koga,Schneller
, p. 5861 - 5864 (2007/10/02)
The synthesis of the adenine derivative (±)-(1α,2β,4α)-4-(6-amino-9H-purin-9-yl)-1,2-cyclopentanediol (2) and its hypoxanthine analogue (3) as carbocyclic nucleosides lacking the 5'-methylene is described in 7 steps from 3-cyclopenten-1-ylamine hydrochlor