132123-39-8

Basic information

• Product Name: 4''-(TRANS-4-PROPYLCYCLOHEXYL)-3,4,5-TRIFLUORO-BIPHENYL
• Synonyms: 4''-(TRANS-4-PROPYLCYCLOHEXYL)-3,4,5-TRIFLUORO-BIPHENYL;3,4,5-Trifluoro-4`-(4-propyl-cyclohexyl)biphenyl;3,4,5-Trifluoro-4'-(trans-4-propylcyclohexyl)- 1,1'-biphenyl;[3,4,5-trifluoro-4-(4-propylcyclohexyl)cyclohexa-1,5-dien-1-yl]benzene;trans-3,4,5-Trifluoro-4'-(4-n-propylcyclohexyl)biphenyl, 99%;trans-3,4,5-Trifluoro-4'-(4-propylcyclohexyl)biphenyl;3,4,5-Trifluoro-4'-(trans-4-propylcyclohexyl)biphenyl;3,4,5-Trifluoro-4'-((1s,4r)-4-propylcyclohexyl)biphenyl
• CAS NO: 132123-39-8
• Molecular Formula: C21H23F3
• Molecular Weight: 332.407
• Mol File: 132123-39-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 40.0 to 44.0 °C
• Boiling Point: 402.5 °C at 760 mmHg
• Flash Point: 228.4 °C
• Appearance: /
• Density: 1.098 g/cm³
• Vapor Pressure: 0-0.007Pa at 20-50℃
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 4''-(TRANS-4-PROPYLCYCLOHEXYL)-3,4,5-TRIFLUORO-BIPHENYL(CAS DataBase Reference)
• NIST Chemistry Reference: 4''-(TRANS-4-PROPYLCYCLOHEXYL)-3,4,5-TRIFLUORO-BIPHENYL(132123-39-8)
• EPA Substance Registry System: 4''-(TRANS-4-PROPYLCYCLOHEXYL)-3,4,5-TRIFLUORO-BIPHENYL(132123-39-8)

Safety Data

• Hazardous Substances Data: 132123-39-8(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

It is employed as a pharmaceutical intermediate.

Upstream product

• 86579-53-5 1-(trans-4-n-propylcyclohexyl)-4-bromobenzene 
• 143418-49-9 3,4,5-trifluorophenylboronic acid 
• 86579-53-5 4-(4-propylcyclohexyl)-1-bromobenzene 
• 138526-69-9 3,4,5-trifluoro-1-bromobenzene 

Relevant articles and documents

Suzuki cross-coupling reactions of aryl chlorides using [Cl 2Pd(COD)]/piperazine derivative under microwave conditions

A new strategy to significantly improve the efficiency of Suzuki reactions was achieved under microwave irradiation. [Cl2Pd(COD)]/piperazine derivative 1 catalyzed aryl chlorides with phenylboronic acid in methanol (50%) affording excellent yields under aerobic conditions. Application of this strategy to the synthesis of liquid crystal material is also described.

An aerobic and very fast Pd/C-catalyzed ligand-free and aqueous Suzuki reaction under mild conditions

An aerobic, ligand-free Suzuki reaction catalyzed by Pd/C in aqueous media has been developed. This method is a very simple, efficient and mild protocol for the cross-coupling of aryl bromides with arylboronic acids, and the reactions proceeded smoothly in excellent yields within short reaction times. Control experiments demonstrated that the Pd/C-catalyzed Suzuki reaction was much quicker when performed in air or oxygen than in nitrogen. Furthermore, this protocol could be used for the synthesis of fluorinated liquid-crystalline compounds. The Pd/C catalyst could be recovered and recycled efficiently at least ten times without significant loss of catalytic activity. Copyright