1322062-76-9 Usage
General Description
Propanamide, 2-amino-3-methoxy-N-(phenylmethyl)-, hydrochloride (1:1), (2R)-, also known as Levomethadone hydrochloride, is a chemical compound used as an opioid analgesic and medication for opioid use disorder. As a hydrochloride salt, it is typically administered orally or through injection and is prescribed to manage moderate to severe pain. Levomethadone works by binding to the opioid receptors in the brain and spinal cord, reducing the perception of pain and producing a calming effect. It is classified as a Schedule II controlled substance due to its high potential for abuse and addiction. This chemical compound is regulated and prescribed under strict supervision by healthcare professionals.
Check Digit Verification of cas no
The CAS Registry Mumber 1322062-76-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,2,2,0,6 and 2 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1322062-76:
(9*1)+(8*3)+(7*2)+(6*2)+(5*0)+(4*6)+(3*2)+(2*7)+(1*6)=109
109 % 10 = 9
So 1322062-76-9 is a valid CAS Registry Number.
1322062-76-9Relevant articles and documents
Improved Synthesis and Impurity Identification of (R)-Lacosamide
Yang, Anjiang,Hu, Feifei,Li, Zhong,Chen, Mengdi,Cai, Jianguang,Wang, Linghui,Zhang, Tao,Zhao, Chuanmeng,Zhang, Fuli
, p. 818 - 824 (2019/04/01)
An improved synthesis of Lacosamide 1 with high purity has been developed. Critical parameters of each step were identified as well as the impurities generated. Moreover, a creative method to improve chiral purity and stability of the key intermediate (R)-2-amino-N-benzyl-3-methoxypropionamide 10 by forming salt with an achiral acid (phosphoric acid) was discovered to ensure the chiral purity of (R)-Lacosamide. Phosphoric acid was further developed for the deprotection of the Boc group.
