132294-25-8

Basic information

• Product Name: <1R-(1α,2β,3β)>-3-hydroxy-1,2-cyclobutanedimethanol 1,2-dibenzoate ester
• Synonyms: <1R-(1α,2β,3β)>-3-hydroxy-1,2-cyclobutanedimethanol 1,2-dibenzoate ester
• CAS NO: 132294-25-8
• Molecular Weight: 340.376
• Mol File: 132294-25-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: <1R-(1α,2β,3β)>-3-hydroxy-1,2-cyclobutanedimethanol 1,2-dibenzoate ester(CAS DataBase Reference)
• NIST Chemistry Reference: <1R-(1α,2β,3β)>-3-hydroxy-1,2-cyclobutanedimethanol 1,2-dibenzoate ester(132294-25-8)
• EPA Substance Registry System: <1R-(1α,2β,3β)>-3-hydroxy-1,2-cyclobutanedimethanol 1,2-dibenzoate ester(132294-25-8)

Safety Data

• Hazardous Substances Data: 132294-25-8(Hazardous Substances Data)

Upstream product

• 124770-80-5 trans-2,3-bis(benzoyloxymethyl)cyclobutanone 
• 124770-79-2 C₂₄H₂₈O₆ 
• 127696-10-0 trans-3,3-diethoxy-1,2-cyclobutanedicarboxylic acid diethyl ester 
• 126261-70-9 (+/-)-trans-1,2-bis-(3,3-diethoxycyclobutylen)methanol 
• 132178-71-3 trans-3,3-diethoxy-1,2-cyclobutanedicarboxylic acid 
• 132294-24-7 (2R-trans)-2,3-bis<(benzoyloxy)methyl>cyclobutanone 
• 132178-72-4 <1S-<1α(S^*),2β(S^*)>>-3,3-diethoxy-N,N'-bis-(2-hydroxy-1-phenylethyl)-1,2-cyclobutanedicarboxamide 
• 132178-74-6 C₃₈H₆₀N₄O₈Si₂ 
• 132178-73-5 [1S-[1α(S*),2β(S*)]]-N,N'-Bis[2-[[(1,1-dimethylethyl) dimethylsilyl]oxy]-1-phenylethyl]-3,3-diethoxy-1,2-cyclobutanedicarboxamide 

Downstream Products

• 126261-74-3 (1α,2β,3β)-3-<<(4-methylphenyl)sulfonyl>oxy>-1,2-cyclobutanedimethanol, dibenzoate ester 
• 132294-27-0 <1R-(1α,2β,3α)>-3-<2-amino-6-(phenylmethoxy)-9H-purin-9-yl>-1,2-cyclobutanedimethanol 1,2-dibenzoate ester 
• 132294-28-1 <1S-(1α,2β,3α)>-6-amino-9-<2,3-bis(hydroxymethyl)cyclobutyl>purine 2,3-dibenzoate ester 
• 132294-26-9 <1R-(1α,2β,3β)>-3-<<(4-methylphenyl)sulfonyl>oxy>-1,2-cyclobutanedimethanol dibenzoate ester 
• 126261-75-4 C₃₂H₂₉N₅O₅ 
• 126062-18-8 (+/-)-9-<(1β,2α,3β)-2,3-bis(hydroxymethyl)-1-cyclobutyl>guanine 

Relevant articles and documents

CYCLOBUTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS

Described herein are cyclobutyl nucleoside analogs of Formula (I), pharmaceutical compositions that include one or more cyclobutyl nucleoside analogs and methods of using the same to treat HBV, HDV and/or HIV.

Synthesis of SQ-33,054, a novel cyclobutane nucleoside with potent antiviral activity

The racemic, guanine-containing cyclobutane nucleoside SQ-33,054 (3) was synthesized in 8 steps from the cyclobutane diester 4.