13230-43-8 Usage
Chemical class
Imidazole derivative
Structural features
Allyl group attached to the imidazole ring
Methyl group at the 2nd position of the imidazole ring
Nitro group at the 5th position of the imidazole ring
Applications
Intermediate in the synthesis of pharmaceuticals and agrochemicals
Used in the production of antifungal and antibacterial agents
Biological properties
Exhibits antimicrobial properties
Potential use in the treatment of certain diseases
Precursor to other biologically active compounds
Reactivity and biological activity
The allyl and nitro groups contribute to its reactivity and biological activity
Versatile and important chemical in the pharmaceutical and agrochemical industries
Check Digit Verification of cas no
The CAS Registry Mumber 13230-43-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,2,3 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13230-43:
(7*1)+(6*3)+(5*2)+(4*3)+(3*0)+(2*4)+(1*3)=58
58 % 10 = 8
So 13230-43-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H9N3O2/c1-3-4-9-6(2)8-5-7(9)10(11)12/h3,5H,1,4H2,2H3
13230-43-8Relevant articles and documents
Regioselective Alkylation of 4(5)-Nitro-1H-Imidazoles in Acidic Media: Study of Temperature Effects
Rao, A. K. S. Bhujanga,Rao, C. Gundu,Singh, B. B.
, p. 2399 - 2402 (2007/10/02)
Alkylation of 4(5)-nitro-1H-imidazoles in acidic media with reactive alkylating agents such as benzyl chloride and allyl bromide resulted in the predominant formation of the 5-nitro isomers at lower temperatures (75 deg C) and the 4-nitro isomers at higher temperatures (140 deg C).With less reactive alkylating agents, only the 5-nitro isomers were produced irrespective of temperature.The mechanism was shown to involve quaternization of the initially formed 1-alkyl-5-nitro-1H-imidazoles followed by preferential dealkylation to yield the thermodynamically more stable 4-nitro-1H-imidazoles.
