1323137-09-2

Basic information

• Product Name: [Pd(Amphos)(cinnamyl)Cl]
• Synonyms: [Pd(Amphos)(cinnamyl)Cl]
• CAS NO: 1323137-09-2
• Molecular Weight: 524.422
• Mol File: 1323137-09-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [Pd(Amphos)(cinnamyl)Cl](CAS DataBase Reference)
• NIST Chemistry Reference: [Pd(Amphos)(cinnamyl)Cl](1323137-09-2)
• EPA Substance Registry System: [Pd(Amphos)(cinnamyl)Cl](1323137-09-2)

Safety Data

• Hazardous Substances Data: 1323137-09-2(Hazardous Substances Data)

Upstream product

• 932710-63-9 (4-(N,N-dimethylamino)phenyl)-di-tert-butylphosphine 

Relevant articles and documents

Highly active well-defined palladium precatalysts for the efficient amination of aryl chlorides

The efficient preparation of [Pd(Amphos)(cinnamyl)Cl)] and [Pd(Amphos)(TFA)(κ2-N,C-C6H4-CH 2NMe2)] (Amphos = 4-(di-tert-butylphosphino)-N,N- dimethylaniline and TFA = trifluoroacetate), two new well-defined palladium precatalysts, is reported. These complexes prove highly active in the Buchwald-Hartwig amination reaction, allowing the coupling of a wide range of (hetero)aryl chlorides, including unactivated, neutral, and sterically hindered substrates, with a wide range of amines, including primary and secondary amines. Finally, the catalytic systems have proven efficient at low catalyst loadings ranging from 0.1 to 0.3 mol %.