1325732-05-5Relevant articles and documents
The catalytic asymmetric 1,3-dipolar cycloaddition of ynones with azomethine ylides
Shi, Feng,Luo, Shi-Wei,Tao, Zhong-Lin,He, Long,Yu, Jie,Tu, Shu-Jiang,Gong, Liu-Zhu
, p. 4680 - 4683 (2011/11/06)
The first catalytic asymmetric 1,3-dipolar cycloaddition of electron-deficient carbon-carbon triple bonds with azomethine ylides has been established. This reaction provides an unprecedented approach to access novel 2,5-dihydropyrrole derivatives with potential bioactivities in perfect enantioselectivities of up to >99% ee.